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Homework #3 due now Bonus #2 posted Homework #4 is due 12/3/07 (only if needed) No class W 11/21
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Genotype Phenotype Dominant Recessive
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Human blood types AA or AO BB or BO AB OO
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If Frank has B blood type,
his Dad has A blood type, And his Mom has B blood type… Should Frank be worried?
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Mom=B blood BB or BO Dad=A blood AA or AO possible genotypes
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Mom=B blood BB or BO Dad=A blood AA or AO all B / 50% B and 50% O
possible genotypes all B / 50% B and 50% O all A / 50% A and 50% O Gametes
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Mom=B blood BB or BO Dad=A blood AA or AO Gametes all B / 50% B and
possible genotypes Gametes all B / 50% B and 50% O all A / 50% A and 50% O Frank can be BO = B blood …no worries
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Mom=B blood BB or BO Dad=A blood AA Gametes all B / 50% B and 50% O
Grandparents AB and AB Mom=B blood BB or BO Dad=A blood AA possible genotypes Gametes all B / 50% B and 50% O all A Frank can be BO or BB = B blood …Uh-Oh
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Pedigree, tracing the genetic past
Dom. Rec. Rec. Dom.
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We can also predict the future
Fig 2.12
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Inheritance of blood types
Mom = AB Dad = AB
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Inheritance of blood types
Mom = AB Dad = AB Gametes: A or B A or B
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Mom = AB Dad = AB A or B A or B Gametes: Dad A or B 25% AA 50% AB
Inheritance of blood types Mom = AB Dad = AB A or B A or B Gametes: Dad A or B Chance of each phenotype for each offspring 25% AA 50% AB 25% BB AA A or B AB Mom AB BB
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Single genes controlling a single trait are unusual
Single genes controlling a single trait are unusual. Inheritance of most genes/traits is much more complex… Dom. Rec. Rec. Dom.
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Genotype Phenotype Genes code for proteins (or RNA). These gene products give rise to traits…
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Human blood types AA or AO BB or BO AB OO
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It is rarely this simple.
Genotype Phenotype Genes code for proteins (or RNA). These gene products give rise to traits… It is rarely this simple. Figs
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Incomplete dominance givers rise to blending.
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Human blood types AA or AO BB or BO AB (Codominance) OO
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Sex determination is normally inherited by whole chromosomes or by number of chromosomes.
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X/Y chromosomes in humans
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The X chromosome has many genes; the Y chromosome only has genes for maleness.
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Human sex chromosomes Fig 2.25
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X/Y chromosomes in humans should give rise to equal numbers of males and females
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105 males : 100 females (live births)
Why?
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105 males : 100 females (live births)
Why?
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Sex-linked traits are genes located on the X chromosome
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Color Blind Test
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No one affected, female carriers
Sex-linked traits: Genes on the X chromosome A= normal; a= colorblind colorblind normal No one affected, female carriers similar to Fig 2.27
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50% of males affected, 0 % females affected
Sex-linked traits: Genes on the X chromosome A= normal; a= colorblind normal normal 50% of males affected, 0 % females affected similar to Fig 2.27
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50% males affected, 50% females affected
Sex-linked traits: Genes on the X chromosome A= normal; a= colorblind colorblind normal 50% males affected, 50% females affected similar to Fig 2.27
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Sex-linked traits: Genes on the X chromosome A= normal ; a= colorblind
No one affected, female carriers 50% of males affected, 0 % female affected 50% males affected, 50% females affected similar to Fig 2.27
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Homework #3 due now Bonus #2 posted Homework #4 is due 12/3/07 (only if needed) No class W 11/21
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