1. 2.01 Remember the structures of the circulatory system: blood
Hematology
Use worksheet page 96: structures of blood (I did not use - too many copies)
Use worksheet page 115 for blood types ( I did use this with blood typing activity)

2. 2.01 Remember the structures of the circulatory system
Essential questions
What are the structures of blood?
What is hematology?
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3. 2.01 Remember the structures of the circulatory system
Blood
Hemat- = blood
-ology = the study of
The average adult has
8 – 10 pints.
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4. 2.01 Remember the structures of the circulatory system
Blood
One drop of blood contains:
5 million RBCs
250, ,000 platelets
7,500 WBCs
Red blood cells live 120 days.
New blood cells created 2 million per second!
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5. Structures (Components) of the blood
Plasma
Erythrocytes
Leukocytes
Thrombocytes
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6. 2.01 Remeber the structures of the circulatory system
Plasma
Liquid portion without cellular components
Straw-colored liquid
55% of the blood’s volume
Water
Plasma proteins
Nutrients
Electrolytes
Hormones, vitamins, and enzymes
Waste products
Plasma
Cellular elements 6
2.01 Remeber the structures of the circulatory system

7. 2.01 Remember the structures of the circulatory system
Plasma proteins
Fibrinogen
Albumin
Globulin
Gamma globulin
Prothrombin
Plasma
Cellular elements
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8. Plasma proteins Fibrinogen Helps with blood clotting Made in liver
Albumin
Helps blood to coagulate
Needs vitamin K for prothrombin synthesis
Globulin
Gamma Globulin
Prothrombin - helps blood to coagulate, needs vitamin K for prothrombin synthesis
Plasma
Cellular elements 8

9. 2.01 Remember the structures of the circulatory system
Erythrocytes
Biconcave disk
Hemoglobin
Hemo (blood)
Globin (protein)
Blood protein that gives the cells its red color
Transportation
Oxygen to cells
Carbon dioxide away from cells
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10. 2.01 Remember the structures of the circulatory system
Leukocytes (WBC)
Fight Infection
Larger than erythrocytes
Leuk/o/cytes – white cells
Five types
Neutrophil
Monocyte
Lymphocyte
Eosinophil
basophil
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11. 2.01 Remember the structures of the circulatory system
Leukocytes
Agranulocytes
(without granules)
Lymphocytes
Monocytes
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12. 2.01 Remember the structures of the circulatory system
Leukocytes
Granulocytes
With granules
Neutrophils
Eosinophils
Basophils
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13. 2.01 Remember the structures of the circulatory system
Thrombocytes
Smallest of solid components of blood
Synthesized in red marrow
Not cells, composed of fragments of megakaryocytes
Necessary for the initiation of the blood clotting process
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14. Life span of blood cells...
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15. 2.01 Remember the structures of the circulatory system
Blood types
What are the types of blood?
Inherited from parents
Determined by presence or absence of an antigen on the surface of the red blood cell
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16. 2.01 Remember the structures of the circulatory system
Check your knowledge of medical history...
In 1901, the Austrian immunologist Karl Landsteiner discovered that blood may be grouped into four main types.
Based on the reaction that resulted when blood from different individuals were mixed.
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17. 2.01 Remember the structures of the circulatory system
Blood types
Blood from the donor to the recipient must be compatible
The problem occurs when the protein (antigen) outer layer of RBC of a donor becomes coagulated or agglutinated (clumped) with the plasma proteins (agglutinins or antibodies ) of the recipient
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18. 2.01 Remember the structures of the circulatory system
Blood types
There are four different types of blood A B AB O
They are determined by the protein (antigen) found on the RBC
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19. 2.01 Remember the structures of the circulatory system
Blood types
Type A RBC’s have A antigen with B antibodies
Type B RBC’s have B antigen with A antibodies
Type AB RBC’s have AB antigen with no antibodies
Type O RBC’s have (zero) antigen with A and B antibodies
AB is universal recipient
O is universal donor
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20. 2.01 Remember the structures of the circulatory system
Blood types
AB is universal recipient:
Universal recipient since it does not have agglutinins (antibodies) in the plasma
O is universal donor
Universal donor since it does not have antigens (proteins) on the surface of the RBC’s
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21. 2.01 Remember the structures of the circulatory system
Rh factor
Rhesus (Rh) factor is an inherited trait that refers to a specific protein found on the surface of red blood cells (antigen).
Blood used in transfusions must match donors for Rh status as well as for ABO blood type.
Although Rh factor doesn't affect the patient’s health, it can affect pregnancy.
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22. 2.01 Remember the structures of the circulatory system
Rh factor
In 1940, the Rh factor was discovered as a result of studying Rhesus monkeys.
When blood from monkeys was injected into rabbits and guinea pigs, it clotted.
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23. 2.01 Remember the structures of the circulatory system
Rh factor
If the blood has the protein, the patient is Rh positive.
If the blood lacks the protein, the patient is Rh negative.
Did you know???
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24. What is blood: https://www.youtube.com/watch?v=JRnaSfdjdl0
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