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Published byΟφέλια Μάγκας Modified over 5 years ago
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Improved prediction of lobar perfusion contribution using technetium-99m–labeled macroaggregate of albumin single photon emission computed tomography/computed tomography with attenuation correction Lauren K. Toney, MS, MD, Michelle Wanner, BS, Robert S. Miyaoka, PhD, Adam M. Alessio, PhD, Douglas E. Wood, MD, Hubert Vesselle, PhD, MD The Journal of Thoracic and Cardiovascular Surgery Volume 148, Issue 5, Pages (November 2014) DOI: /j.jtcvs Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions
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Figure 1 Upper, Technetium-99m–labeled macroaggregate of albumin (Tc-99 MAA) lung perfusion with planar perfusion and lower, single photon emission computed tomography/computed tomography (SPECT/CT) with attenuation correction. In planar perfusion scintigraphy, regional quantitation of lung perfusion is assessed in the traditional method by drawing 3 regions-of-interest of equal size over each lung, thus dividing the lung into upper, middle, and lower lung zones. The SPECT/CT method provides more anatomically accurate lobar perfusion quantitation. The CT images are viewed in lung windows to identify fissures such that 3-dimensional volumes of interest (VOIs) are drawn around each lobe. The CT-derived VOIs are then projected onto the co-registered attenuation-corrected SPECT images to obtain the relative lobar perfusion contribution. The Journal of Thoracic and Cardiovascular Surgery , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions
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Figure 2 Concordance between single photon emission computed tomography/computed tomography (SPECT/CT) and planar-derived estimates of lobar perfusion is displayed graphically for upper row, planar partition 1, and lower row, partition 2 for the left and right lung. LUL, Left upper lobe; LLL, left lower lobe; RUL, right upper lobe; RML, right middle lobe; RLL, right lower lobe. Each plotted point represents, for a given patient, the comparison of SPECT/CT and planar methods with respect to a given lobe. The discordance between these 2 methods increases as the distance away from the line of unity (y = x) for each plotted point increases. Note that the 2 right graphs are identical, because the 2 planar partition methods treat the right lung identically. The Journal of Thoracic and Cardiovascular Surgery , DOI: ( /j.jtcvs ) Copyright © 2014 The American Association for Thoracic Surgery Terms and Conditions
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