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Age and liver transplantation

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Presentation on theme: "Age and liver transplantation"— Presentation transcript:

1 Age and liver transplantation
François Durand, Josh Levitsky, François Cauchy, Hélène Gilgenkrantz, Olivier Soubrane, Claire Francoz  Journal of Hepatology  Volume 70, Issue 4, Pages (April 2019) DOI: /j.jhep Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

2 Fig. 1 Distribution of recipients by age categories in the United States and Europe. (A) Data from the United Network for Organ Sharing ( (B) Data from the European Liver Transplant Registry ( Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

3 Fig. 2 Main contributors to morbidity and mortality in older liver transplant recipients. CKD, chronic kidney disease. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

4 Fig. 3 Major modifications of the liver with physiological aging. *Tetraploid hepatocytes. CMA, chaperone-mediated autophagy; DC, dendritic cell. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

5 Fig. 4 Distribution of donors and recipients by age categories in the United States and Europe in (A) Data from the United Network for Organ Sharing ( (B) Data from the European Liver Transplant Registry ( Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions

6 Fig. 5 Examples of possible implications age limits in candidates for transplantation and age matching between the donor and the recipient according to different allocation policies. MELD, model for end-stage liver disease. Journal of Hepatology  , DOI: ( /j.jhep ) Copyright © 2018 European Association for the Study of the Liver Terms and Conditions


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