Presentation is loading. Please wait.

Presentation is loading. Please wait.

L. Gato-Calvo, Á. Vela-Anero, E. Loures-Fraga, C. Ruiz Romero, F. J

Similar presentations


Presentation on theme: "L. Gato-Calvo, Á. Vela-Anero, E. Loures-Fraga, C. Ruiz Romero, F. J"— Presentation transcript:

1 Proliferative and Anti-Inflammatory Effect of Platelet-Rich Plasma on Osteoarthritic Chondrocytes 
L. Gato-Calvo, Á. Vela-Anero, E. Loures-Fraga, C. Ruiz Romero, F.J. Blanco, E.F. Burguera  Osteoarthritis and Cartilage  Volume 25, Pages S270-S271 (April 2017) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1. Chondrocyte proliferation in DMEM 10% FBS (Basal) and DMEM 0% + 10% PRPr according to cell count (a), protein count (b) and cell activity measured with alamarBlue (c). Cell counts were 0.3–2.6 times bigger in PRPr-supplemented medium. Similar trends were found in protein counts and cell activity measurements. *p-value < 0.05, **p-value < 0.01. Osteoarthritis and Cartilage  , S270-S271DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2. Inflammatory response of chondrocytes after 48 h of co-estimulation with IL-1B and PRPr. Optical microscopy (a) shows the recovery of basal morphology under the effect of PRPr. Pro-inflammatory gene markers (b) were downregulated by 60–80% on average in knee CH, with top reductions of 95–99% for iNOS and MMP-13. Data are expressed as mean ± SEM. ***p-value < Osteoarthritis and Cartilage  , S270-S271DOI: ( /j.joca ) Copyright © Terms and Conditions


Download ppt "L. Gato-Calvo, Á. Vela-Anero, E. Loures-Fraga, C. Ruiz Romero, F. J"

Similar presentations


Ads by Google