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Exceptional Human Longevity

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Presentation on theme: "Exceptional Human Longevity"— Presentation transcript:

1 Exceptional Human Longevity
Robert J. Pignolo, MD, PhD  Mayo Clinic Proceedings  Volume 94, Issue 1, Pages (January 2019) DOI: /j.mayocp Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Survivorship according to mortality rates experienced or projected in persons born in England and Wales. Although mean life span has increased, maximum life span has remained essentially unchanged. From the UK Office for National Statistics,6 with permission granted by the United Kingdom Licensing Framework, Open Government License. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 Possible scenarios for future morbidity and longevity. From Ann Intern Med, Fries JF, Measuring and monitoring success in compressing morbidity, Volume No. 139, Issue No. 5 (Part 2), Pages Copyright © 2003 American College of Physicians. All Rights Reserved. Reprinted with the permission of American College of Physicians, Inc. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions

4 Figure 3 Multiple pathways to exceptional longevity. Shown are putative relationships among factors associated with extreme long life. Mayo Clinic Proceedings  , DOI: ( /j.mayocp ) Copyright © 2018 Mayo Foundation for Medical Education and Research Terms and Conditions


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