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Ferret Interneurons Defy Expectations

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1 Ferret Interneurons Defy Expectations
Petr Znamenskiy, Sonja B. Hofer  Neuron  Volume 93, Issue 5, Pages (March 2017) DOI: /j.neuron Copyright © 2017 Elsevier Inc. Terms and Conditions

2 Figure 1 Models of Connectivity of Inhibitory Interneurons
(A) Cells with diverse orientation preferences are intermingled in mouse visual cortex. (B) Orientation preference is mapped smoothly in ferret visual cortex but is heterogeneous in regions such as pinwheel centers (dashed line), which like mouse V1 contain neurons with a broad range of selectivities. (C) Nonspecific connectivity from excitatory to inhibitory neurons predicts weak orientation selectivity in mouse V1 and heterogeneous regions of ferret V1. (D and E) Specific connectivity (D) or specific synaptic weights (E) can give rise to selective interneuron responses in regions with heterogeneous excitatory cell tuning. Neuron  , DOI: ( /j.neuron ) Copyright © 2017 Elsevier Inc. Terms and Conditions

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