1. A Comparison of Symptom Severity and Bolus Retention With Chicago Classification Esophageal Pressure Topography Metrics in Patients With Achalasia 
Frédéric Nicodème, Annemijn de Ruigh, Yinglian Xiao, Shankar Rajeswaran, Ezra N. Teitelbaum, Eric S. Hungness, Peter J. Kahrilas, John E. Pandolfino 
Clinical Gastroenterology and Hepatology 
Volume 11, Issue 2, Pages (February 2013)
DOI: /j.cgh
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2. Figure 1
The 4 potential HRM patterns after treatment of type 1 or type 2 achalasia. (A and B) Persistent achalasia patterns. (C and D) Resolved achalasia patterns: (C) absent peristalsis or (D) weak peristalsis.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh )
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3. Figure 2
Examples of TBE and HRM studies for untreated patients. The TBE column height and width do not differentiate type 1 and type 2 achalasia.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh )
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4. Figure 3
TBE column height at 5 minutes and ES in patient groups defined by normal or abnormal EGJ metrics: (A) IRP, (B) resting EGJ pressure, and (C) nadir EGJ relaxation pressure. Note that only the IRP (<15 or ≥15 mm Hg) segregates the patients into 2 significantly different groups (P < .05). LES, lower esophageal sphincter pressure.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh )
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5. Figure 4
Comparison of IRP (mm Hg), TBE column height at 5 minutes (cm), and ES (median) among patients subdivided by post-treatment EPT pattern (types 1 and 2 achalasia, absent peristalsis, and weak peristalsis). The values of the 3 variables were lower in patients with a resolved achalasia pattern (P < .05), suggesting this was indicative of consistently better outcome. The group that evolved to weak peristalsis appeared to have the best outcome with a significantly lower barium column height at 5 minutes (P < .05) and a trend toward a lower ES compared with the other 3 groups.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh )
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6. Figure 5
Relationship between IRP (mm Hg) and TBE column height at 5 minutes (cm) defined by post-treatment ES and HRM pattern. Resolution of the HRM achalasia pattern was associated with a greater likelihood to have an ES less than 3. There were no instances in which the IRP was abnormal and complete emptying occurred. Patients also tended to have better outcomes when both the IRP and barium column height were less than the cut-off values (IRP <15 mm Hg, TBE column height <5 cm), but there were 2 patients who continued to have symptoms despite minimal bolus retention and low IRP values.
Clinical Gastroenterology and Hepatology  , DOI: ( /j.cgh )
Copyright © 2013 AGA Institute Terms and Conditions