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Volume 151, Issue 1, Pages (October 2018)

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1 Volume 151, Issue 1, Pages 10-17 (October 2018)
Patient inflammatory status and CD4+/CD8+ intraepithelial tumor lymphocyte infiltration are predictors of outcomes in high-grade serous ovarian cancer  Mauricio P. Pinto, Carlos Balmaceda, Maria L. Bravo, Sumie Kato, Alejandra Villarroel, Gareth I. Owen, Juan Carlos Roa, Mauricio A. Cuello, Carolina Ibañez  Gynecologic Oncology  Volume 151, Issue 1, Pages (October 2018) DOI: /j.ygyno Copyright © 2018 The Authors Terms and Conditions

2 Fig. 1 Post-operative systemic inflammation in ovarian cancer patients determines overall survival rates. A. Kaplan-Meier curve of ovarian cancer patients with elevated (≥3.0 ratio) or normal (<3.0) NLR levels (p = 0.04). B. Kaplan-Meier curve of ovarian cancer patients with elevated (≥220 mg/dl) or normal (<220 mg/dl) serum LDH levels (p = 0.02). Gynecologic Oncology  , 10-17DOI: ( /j.ygyno ) Copyright © 2018 The Authors Terms and Conditions

3 Fig. 2 Representative images of intraepithelial TILs and PDL1+ tumors. Left panels show CD3+ (upper), CD4+ (middle), and CD8+ (lower) intraepithelial TILs. Right panels show representative examples of PDL1 expression in cancer cell membrane categorized as PDL1+ (upper), PDL1++ (middle) and PDL1+++ (lower). Bottom right insets show membrane stain in further detail. Magnification bar is 200 μm. Gynecologic Oncology  , 10-17DOI: ( /j.ygyno ) Copyright © 2018 The Authors Terms and Conditions


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