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Characterization of pro-apoptotic and matrix-degradative gene expression following induction of osteoarthritis in mature and aged rabbits  Dr. C.M. Robertson,

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Presentation on theme: "Characterization of pro-apoptotic and matrix-degradative gene expression following induction of osteoarthritis in mature and aged rabbits  Dr. C.M. Robertson,"— Presentation transcript:

1 Characterization of pro-apoptotic and matrix-degradative gene expression following induction of osteoarthritis in mature and aged rabbits  Dr. C.M. Robertson, M.D., A.T. Pennock, M.D., F.L. Harwood, B.Sc., A.C. Pomerleau, B.A., R.T. Allen, M.D., Ph.D., D. Amiel, Ph.D.  Osteoarthritis and Cartilage  Volume 14, Issue 5, Pages (May 2006) DOI: /j.joca Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

2 Fig. 1 Example of non-OA (grade I) and grade II OA articular cartilage from mature and aged rabbit knee joints. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

3 Fig. 2 Relative mRNA expression of pro-apoptotic genes in mature and aged normal and grade II OA articular cartilage: *P<0.05; normal vs OA. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

4 Fig. 3 Relative mRNA expression of ECM-degrading genes in mature and aged normal and grade II OA articular cartilage. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

5 Fig. 4 Relative mRNA expression of pro-apoptotic genes in mature and aged normal and grade II OA meniscus: *P<0.05; normal vs OA. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions

6 Fig. 5 Relative mRNA expression of ECM-degrading genes in mature and aged normal and grade II OA meniscus. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2005 OsteoArthritis Research Society International Terms and Conditions


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