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Yan Xie, Benjamin Bowe, Tingting Li, Hong Xian, Yan Yan, Ziyad Al-Aly 

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Presentation on theme: "Yan Xie, Benjamin Bowe, Tingting Li, Hong Xian, Yan Yan, Ziyad Al-Aly "— Presentation transcript:

1 Higher blood urea nitrogen is associated with increased risk of incident diabetes mellitus 
Yan Xie, Benjamin Bowe, Tingting Li, Hong Xian, Yan Yan, Ziyad Al-Aly  Kidney International  Volume 93, Issue 3, Pages (March 2018) DOI: /j.kint Copyright © Terms and Conditions

2 Figure 1 Diabetes-free survival curves by time-updated estimated glomerular filtration rate (eGFR) categories (eGFR in ml/min per 1.73 m2). Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions

3 Figure 2 Diabetes-free survival curves by time-updated blood urea nitrogen (BUN) categories; BUN in mg/dl. Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions

4 Figure 3 Spline analysis of the relationship between time-updated estimated glomerular filtration rate (eGFR) and risk of incident diabetes mellitus. The red line represents the hazard ratio, and dashed blue lines represent 95% confidence intervals. eGFR = 120 ml/min per 1.73 m2 was the reference. Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions

5 Figure 4 Spline analysis of the relationship between time-updated blood urea nitrogen (BUN) and risk of incident diabetes mellitus. The red line represents the hazard ratio, and dashed blue lines represent 95% confidence intervals. BUN = 5 mg/dl was the reference. Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions

6 Figure 5 Spline analysis of risk of incident diabetes mellitus including both time-updated estimated glomerular filtration rate (eGFR) and blood urea nitrogen (BUN). eGFR = 120 ml/min per 1.73 m2 and BUN = 5 mg/dl were the reference points. Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions

7 Figure 6 Diabetes-free survival curves by baseline blood urea nitrogen (BUN) categories; BUN in mg/dl. Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions

8 Figure 7 Spline analysis of the relationship between baseline blood urea nitrogen (BUN) and risk of incident diabetes mellitus. The red line represents the hazard ratio, and dashed blue lines represent 95% confidence intervals. BUN = 5 mg/dl was the reference. Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions

9 Figure 8 Flowchart of cohort assembly. VA, Veterans Affairs.
Kidney International  , DOI: ( /j.kint ) Copyright © Terms and Conditions


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