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A Trojan Horse for Human Immunodeficiency Virus

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1 A Trojan Horse for Human Immunodeficiency Virus
Silvia Catuogno, Carla Lucia Esposito, Vittorio de Franciscis  Chemistry & Biology  Volume 22, Issue 3, Pages (March 2015) DOI: /j.chembiol Copyright © 2015 Elsevier Ltd Terms and Conditions

2 Figure 1 G-3 Aptamer and G-3-TNPO 3 Chimera Mode of Action
(A) G3 aptamer specifically binds CCR5, inhibiting HIV viral entry. (B) G-3-TNPO3 chimera combines G-3 aptamer function with TNPO3 gene silencing, resulting in a dual inhibitory effect on HIV-1 entry and replication. Chemistry & Biology  , DOI: ( /j.chembiol ) Copyright © 2015 Elsevier Ltd Terms and Conditions

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