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Volume 4, Pages 109-116 (October 2018)
Prophylactic Intravenous Hydration to Protect Renal Function From Intravascular Iodinated Contrast Material (AMACING): Long-term Results of a Prospective, Randomised, Controlled Trial Estelle C. Nijssen, Patty J. Nelemans, Roger J. Rennenberg, Vincent van Ommen, Joachim E. Wildberger EClinicalMedicine Volume 4, Pages (October 2018) DOI: /j.eclinm Copyright © Terms and Conditions
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Fig. 1 Trial profile. MUMC+ = Maastricht University Medical Centre; eGFR = estimated glomerular filtration rate. H+ group = received standard 0.9% NaCl prophylactic intravenous hydration. H− group = received no prophylaxis. *Our institution follows the screening guidelines that propose renal function needs only be assessed if one of the following risk factors is present: age >60 years, diabetes mellitus, use of nephrotoxic medication, urologic or nephrologic history, hypertension, peripheral vascular/cardiac disease, multiple myeloma/lymphoplasmacytic lymphoma. EClinicalMedicine 2018 4, DOI: ( /j.eclinm ) Copyright © Terms and Conditions
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Fig. 2 Kaplan–Meier Survival Plot for the standard prophylactic treatment (H+) and no prophylactic treatment (H−) groups. Hazard ratio for 1-year risk of death (95% CI to 1.801, n = 660, p = 0.6449). EClinicalMedicine 2018 4, DOI: ( /j.eclinm ) Copyright © Terms and Conditions
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Fig. 3 Observed mean serum creatinine and changes in serum creatinine in the standard prophylactic treatment (H+) and no prophylactic treatment (H−) groups. Error bars show standard deviations. EClinicalMedicine 2018 4, DOI: ( /j.eclinm ) Copyright © Terms and Conditions
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