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Off-pump versus on-pump coronary artery bypass grafting: Insights from the Arterial Revascularization Trial  Umberto Benedetto, MD, PhD, Douglas G. Altman,

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Presentation on theme: "Off-pump versus on-pump coronary artery bypass grafting: Insights from the Arterial Revascularization Trial  Umberto Benedetto, MD, PhD, Douglas G. Altman,"— Presentation transcript:

1 Off-pump versus on-pump coronary artery bypass grafting: Insights from the Arterial Revascularization Trial  Umberto Benedetto, MD, PhD, Douglas G. Altman, DSc, Stephen Gerry, MSc, Alastair Gray, PhD, Belinda Lees, BSc, PhD, Marcus Flather, MD, David P. Taggart, MD, PhD  The Journal of Thoracic and Cardiovascular Surgery  Volume 155, Issue 4, Pages e7 (April 2018) DOI: /j.jtcvs Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Study flow chart for patient inclusion/exclusion. OPCAB, Off-pump coronary artery bypass; ONCAB, on-pump coronary artery bypass. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

3 Figure 2 Five-year cumulative incidence for mortality and MACCE in the matched OPCAB and ONCAB groups. ONCAB, On-pump coronary artery bypass; OPCAB, off-pump coronary artery bypass. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

4 Figure 3 Five-year cardiovascular death, MI, CVA, and revascularization cumulative incidence in the OPCAB and ONCAB groups. CV, Cardiovascular; ONCAB, on-pump coronary artery bypass; OPCAB, off-pump coronary artery bypass; MI, myocardial infarction; CVA, cerebrovascular accident. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

5 Figure E1 Propensity score density before and after matching.
The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

6 Figure E2 Changes in standardized mean difference for baseline characteristics between OPCAB and ONCAB before (red) and after matching (blue). ONCAB, On-pump coronary artery bypass; OPCAB, off-pump coronary artery bypass; PCI, percutaneous coronary intervention; MI, myocardial infarction; LVEF, left ventricular ejection fraction; BITA, bilateral internal thoracic artery; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; LMD, left main disease; CVA, cerebrovascular accident; AF, atrial fibrillation; PVD, peripheral vascular disease; TIA, transient ischemic attack; COPD, chronic obstructive pulmonary disease; RA, radial artery; SVG, saphenous vein graft. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

7 Figure E3 Five-year cumulative incidence for mortality and MACCE in the OPCAB group according to the incidence of conversion to on-pump. OPCAB, Off-pump coronary artery bypass; MACCE, major cardiac and cerebrovascular event. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

8 Figure E4 Five-year cumulative incidence for mortality and MACCE in the OPCAB and ONCAB groups according to surgeon trial OPCAB volume (0 = performing on-pump only; 1-5 = low OPCAB volume; 6-60 = moderate volume; >60 = high volume). OPCAB, Off-pump coronary artery bypass; MACCE, major cardiac and cerebrovascular event. The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

9 Five-year cumulative incidence for mortality in the matched OPCAB and ONCAB groups.
The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

10 Video 1 Off-pump coronary artery bypass grafting. Video available at: The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

11 The Journal of Thoracic and Cardiovascular Surgery 2018 155, 1545-1553
The Journal of Thoracic and Cardiovascular Surgery  , e7DOI: ( /j.jtcvs ) Copyright © 2017 The American Association for Thoracic Surgery Terms and Conditions

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