1. Leukocyte DNA damage after reduced and conventional absorbed radiation doses using 3rd generation dual-source CT technology 
Henning D. Popp, Mathias Meyer, Susanne Brendel, Wiltrud Prinzhorn, Nicole Naumann, Christel Weiss, Wolfgang Seifarth, Stefan O. Schoenberg, Wolf-K. Hofmann, Thomas Henzler, Alice Fabarius 
European Journal of Radiology Open 
Volume 3, Pages (January 2016)
DOI: /j.ejro
Copyright © 2016 The Authors Terms and Conditions

2. Fig. 1
Linear dose dependency of γH2AX foci formation in peripheral blood mononuclear cells (PBMC) after irradiation. PBMC samples were irradiated each with doses of 3mGy, 15mGy and 50mGy by a 3rd generation dual-source CT. Each data point represents the mean γH2AX foci yield±standard error of the mean of 12 different PBMC samples at 5min after irradiation exposure. Mean γH2AX foci yields are corrected by subtracting the mean γH2AX foci yield of the background (0.05 focus per cell).
European Journal of Radiology Open 2016 3, DOI: ( /j.ejro )
Copyright © 2016 The Authors Terms and Conditions

3. Fig. 2
Repair kinetics of DNA double-strand breaks in peripheral blood mononuclear cells (PBMC) after irradiation. PBMC samples were irradiated each with doses of 3mGy, 15mGy and 50mGy by a 3rd generation dual-source CT and analyzed for γH2AX foci yields at 5min, 30min, 5h and 24h after irradiation. All data points represent the mean γH2AX foci yields±standard errors of the mean of three different PBMC samples. Mean γH2AX foci yields are corrected by subtracting the mean γH2AX foci yield of the background (0.05 focus per cell).
European Journal of Radiology Open 2016 3, DOI: ( /j.ejro )
Copyright © 2016 The Authors Terms and Conditions

4. Fig. 3
Fluorescence microscopic images of γH2AX foci in peripheral blood mononuclear cells (PBMC) after irradiation. Images show γH2AX foci (green, Alexa 488) and nuclei (blue, DAPI) of PBMC at 5min after irradiation by a 3rd generation dual-source CT using protocols with absorbed doses of 3mGy, 15mGy and 50mGy, respectively (scale bars 5μm).
European Journal of Radiology Open 2016 3, DOI: ( /j.ejro )
Copyright © 2016 The Authors Terms and Conditions

5. Fig. 4
γH2AX foci yields in peripheral blood mononuclear cells (PBMC) after applying reduced and conventional absorbed doses. Bars represent mean γH2AX foci yields±standard errors of the mean of 12 different PBMC samples at 5min and 24h after application of reduced (3mGy) and conventional absorbed doses (15mGy) using a 3rd generation dual-source CT. Mean γH2AX foci yields are corrected by subtracting the mean γH2AX foci yield of the background (0.05 focus per cell).
European Journal of Radiology Open 2016 3, DOI: ( /j.ejro )
Copyright © 2016 The Authors Terms and Conditions