1. (p = 0.007 for noninferiority)
iFR SWEDEHEART
Trial design: Patients undergoing functional assessment of an indeterminant coronary lesion were randomized to iFR (n = 1,019) versus FFR (n = 1,018).
Results
(p = for noninferiority)
All-cause death, MI, or unplanned revasc. at 12 months: 6.7% of the iFR group versus 6.1% of the FFR group (p = for noninferiority)
Death: 1.5% for iFR vs. 1.2% for FFR
MI: 2.2% for iFR vs. 1.7% for FFR
Unplanned revascularization: 4.6% for iFR vs. 4.6% for FFR %
6.7
6.1
Conclusions
Among patients undergoing functional determination of an indeterminant coronary stenosis for stable or unstable coronary disease, iFR was noninferior to FFR; threshold to revascularize: ≤0.89 for iFR, ≤0.80 for FFR
Adverse cardiac events were similar between study groups
iFR
FFR
Götberg M, et al. N Engl J Med 2017;Mar 18:[Epub]