1. The effects of stenting and endothelial denudation on aneurysm and branch occlusion in experimental aneurysm models 
Tim Darsaut, MD, Fatiha Bouzeghrane, PhD, Igor Salazkin, MD, Sophie Lerouge, PhD, Gilles Soulez, MD, MSc, Guylaine Gevry, BSc, Jean Raymond, MD 
Journal of Vascular Surgery 
Volume 45, Issue 6, Pages (June 2007)
DOI: /j.jvs
Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

2. Fig 1
Endothelial denudation. Vein segments were stained for Factor VIII, showing endothelial cells (arrow in [a]) when intact, but very few endothelial cells when denuded (arrow in [b]). Original magnification 400x.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

3. Fig 2
Angiographic progression of experimental aneurysms. Initial angiograms at the time of stenting (a, c, e, g) are compared with 10-week follow-up angiograms (b, d, f, h) using the lingual (a-d) or carotid bifurcation aneurysm models (e-h) with (c, d, g, h) or without endothelial denudation (a, b, e, f). Note complete (d) or partial (h) occlusion when the aneurysm is denuded, but large residual lesions when the endothelial lining was intact (b, f).
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

4. Fig 3
Macroscopic photography. Typical results for aneurysms treated with stenting alone at 10 weeks (a, c, d) are shown as “en-face” view of aneurysm ostia, (a), and sagittal sections through aneurysm remnant (c, d). Note the patent lingual artery ostium (L) in (c) and the patent channel communicating with an open space within the aneurysm fundus (arrow in d). “En-face” view of completely occluded aneurysm ostium treated with stenting and denudation is shown in (b) for comparison. Neointima formation over branch vessels is shown to be almost completely occlusive in (e) while it spared the ostium of the lingual artery in (f). Partially occluded wide-neck carotid bifurcation aneurysm after endothelial denudation and stenting is shown in (g) (CC, common carotid; LC and RC, left and right carotid arteries; T, organized thrombus; R, residual aneurysm).
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2007 The Society for Vascular Surgery Terms and Conditions

5. Fig 4
Immunopathology. Microphotographs of sectioned aneurysm treated with stenting alone following immunohistochemical staining for smooth muscle actin (a) and endothelial cells (b). In (b), brown-stained endothelial cells line a channel extending from the neck to aneurysm fundus (arrows). Magnification a, 70x; b, 350x.
Journal of Vascular Surgery  , DOI: ( /j.jvs )
Copyright © 2007 The Society for Vascular Surgery Terms and Conditions