1. Crypt Y chromosome fragment resulting from an X;Y translocation in a patient with premature ovarian failure 
De-Hua Cheng, M.Sc., Yue-Qiu Tan, Ph.D., Yu-Fen Di, M.Sc., Lu-Yun Li, M.D., Guang-Xiu Lu, M.D. 
Fertility and Sterility 
Volume 92, Issue 2, Pages 828.e3-828.e6 (August 2009)
DOI: /j.fertnstert
Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions

2. Figure 1
Characterizing the abnormal karyotype of the patient by comparative genomic hybridization (A), G banding (B), and fluorescence in situ hybridization (C).(A) The baseline (middle) ratio is 1.0. The left-sided shift indicates a ratio of 0.8 and the right-sided shift indicates a ratio of 1.2. The result suggested that the patient carried a Y chromosome fragment. (B) Chromosome G banding showed the minute difference between the long arm terminal of the two X chromosomes, but the abnormality could not be determined.(C) Fluorescence in situ hybridization analysis of the patient's metaphase showed a Y chromosome hybridization signal (green) present in the long arm terminal of the derivative X chromosome (triangle) by means of X (red)/Y (green) whole chromosome probes, and only a red signal was observed in the normal X chromosome (arrowhead).
Fertility and Sterility  , 828.e3-828.e6DOI: ( /j.fertnstert )
Copyright © 2009 American Society for Reproductive Medicine Terms and Conditions