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Association of skewed X chromosome inactivation and idiopathic recurrent spontaneous abortion: a systematic review and meta-analysis  Yilun Sui, Qianqian.

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Presentation on theme: "Association of skewed X chromosome inactivation and idiopathic recurrent spontaneous abortion: a systematic review and meta-analysis  Yilun Sui, Qianqian."— Presentation transcript:

1 Association of skewed X chromosome inactivation and idiopathic recurrent spontaneous abortion: a systematic review and meta-analysis  Yilun Sui, Qianqian Chen, Xiaoxi Sun  Reproductive BioMedicine Online  Volume 31, Issue 2, Pages (August 2015) DOI: /j.rbmo Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

2 Figure 1 PRISMA flow chart for study selection.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

3 Figure 2 The association between skewed X chromosome inactivation and idiopathic recurrent spontaneous abortion. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

4 Figure 3 Funnel plot to assess publication and related biases.
Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

5 Figure 4 Association between highly skewed X chromosome inactivation (>85% or ≥85%) and idiopathic recurrent spontaneous abortion. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

6 Figure 5 Association of extremely skewed X chromosome inactivation (>90% or ≥90%) and idiopathic recurrent spontaneous abortion. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

7 Figure 6 Association of extremely skewed X chromosome inactivation (≥95%) and idiopathic recurrent spontaneous abortion. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

8 Figure 7 Association of extremely skewed X chromosome inactivation (>90% or ≥90%) and idiopathic recurrent spontaneous abortion when defined as three or more losses. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

9 Figure 8 Association of extremely skewed X chromosome inactivation (>90% or ≥90%) and idiopathic recurrent spontaneous abortion when defined as two or more losses. Reproductive BioMedicine Online  , DOI: ( /j.rbmo ) Copyright © 2015 Reproductive Healthcare Ltd. Terms and Conditions

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