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Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,

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Presentation on theme: "Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized,"— Presentation transcript:

1 Preliminary assessment of the safety and efficacy of tanezumab in Japanese patients with moderate to severe osteoarthritis of the knee: a randomized, double-blind, dose- escalation, placebo-controlled study  H. Nagashima, M. Suzuki, S. Araki, T. Yamabe, C. Muto  Osteoarthritis and Cartilage  Volume 19, Issue 12, Pages (December 2011) DOI: /j.joca Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

2 Fig. 1 Study design. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

3 Fig. 2 Patient disposition.
Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

4 Fig. 3 MMRM analysis of LS mean change from baseline in WOMAC pain (A), physical function (B), and stiffness (C) subscales, over time, FAS. SE: standard error. Osteoarthritis and Cartilage  , DOI: ( /j.joca ) Copyright © 2011 Osteoarthritis Research Society International Terms and Conditions

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