1. Immune response to vaccination with AVA in healthy human subjects (human immunogenicity study).
Immune response to vaccination with AVA in healthy human subjects (human immunogenicity study). Subjects were immunized with 0.5 ml of AVA via the s.c. route on days 0, 14, and 28. The figure illustrates the TNA NF50 profile over time (GMT ± 95% confidence interval [CI]) in the PP population (n = 121). Individual values below the LOQ (0.064) were replaced with the 1/2 LOQ value (0.032) for statistical analysis purposes.
Boris Ionin et al. Clin. Vaccine Immunol. 2013; doi: /CVI