1. Zc3h10 overexpression boosts mitochondrial function and density in myotubes
Zc3h10 overexpression boosts mitochondrial function and density in myotubes Basal oxygen consumption and mtDNA content in control and Flag‐Zc3h10‐infected C2C12 myotubes 24, 48, and 72 h from differentiation induction. n = 3. Statistical analysis was performed by two‐way ANOVA with Sidak post‐test. *P < 0.05, **P < 0.01, ***P < vs. control.Basal, uncoupled, and maximal uncoupled respiration and complex I, II, and IV activity evaluation 48 h from differentiation induction in control and Flag‐Zc3h10 myotubes. n = 3. Statistical analysis was performed by Student's t‐test. *P < 0.05, **P < 0.01, ***P < vs. control.Data information: n indicates the number of biological replicates. Data are expressed as mean ± SD, and P‐values were calculated from the indicated n independent experiments according to [44].
Matteo Audano et al. EMBO Rep. 2018;19:e45531
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