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The Scientist as Illustrator
Janet H. Iwasa Trends in Immunology Volume 37, Issue 4, Pages (April 2016) DOI: /j.it Copyright © 2016 Elsevier Ltd Terms and Conditions
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Figure 1 Illustrating the Evolution of Iron Piracy. A series of illustrations and animations made in collaboration with Nels Elde and Matthew Barber (University of Utah) depicts how a bacterial transferrin receptor, TbpA, is involved in a molecular ‘arms race’ with the iron-carrying host transferrin protein [3]. (A) A hand drawing of transferrin (Tf) binding to TbpA, located on the bacterial membrane. Dots indicate sites of mutations and compensatory mutations on the binding protein. (B) A still image from the finished animation depicting an evolutionary tree on the left side and the molecular structures on the right side. (C) An editorial illustration on the theme of iron piracy, showing proteins as islands on a treasure map. (D) An editorial illustration showing a contextualized view of the story. In the bloodstream, TbpA is shown on the surface of a bacterium in the lower right, sometimes capturing iron-bound transferrin proteins. Trends in Immunology , DOI: ( /j.it ) Copyright © 2016 Elsevier Ltd Terms and Conditions
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