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Laurent Vecellio, Mohamed E

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1 Disposable versus reusable jet nebulizers for cystic fibrosis treatment with tobramycin 
Laurent Vecellio, Mohamed E. Abdelrahim, Jerome Montharu, Julien Galle, Patrice Diot, Jean-Christophe Dubus  Journal of Cystic Fibrosis  Volume 10, Issue 2, Pages (March 2011) DOI: /j.jcf Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions

2 Fig. 1 Nebulizer image showing the same nebulizer reservoir (Mistyneb) connected with different interfaces resulting in different nebulizers system (A: Mistyneb 2050G, B: Mistyneb 2035G). Journal of Cystic Fibrosis  , 86-92DOI: ( /j.jcf ) Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions

3 Fig. 2 Histogram of in vitro nebulizer performances in terms of fine particle mass predicting the amount of tobramycin deposited in the lungs, extrathoracic dose predicting the amount of tobramycin and inhalable mass (fine particle mass + extrathoracic dose). Journal of Cystic Fibrosis  , 86-92DOI: ( /j.jcf ) Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions

4 Fig. 3 Scintigraphy images obtained with baboons inhaling a tobramycin (Tobi, 300mg/5mL) aerosol nebulized by Pari LC+ operating with Turboboy SX compressor (A), Mistyneb 2035G operating with wall air (8L/min) and Mistyneb 2050G operating with wall air (8L/min). Journal of Cystic Fibrosis  , 86-92DOI: ( /j.jcf ) Copyright © 2010 European Cystic Fibrosis Society. Terms and Conditions


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