Presentation is loading. Please wait.

Presentation is loading. Please wait.

Hiromichi Miwa, MD, Takehisa Matsuda, PhD  Journal of Vascular Surgery 

Published byΖένα Βέργας Modified over 5 years ago

Similar presentations

Presentation on theme: "Hiromichi Miwa, MD, Takehisa Matsuda, PhD  Journal of Vascular Surgery "— Presentation transcript:

1 An integrated approach to the design and engineering of hybrid arterial prostheses 
Hiromichi Miwa, MD, Takehisa Matsuda, PhD  Journal of Vascular Surgery  Volume 19, Issue 4, Pages (April 1994) DOI: /S (94) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 Scanning electron micrograph of preimplanted graft. PU, Polyurethane graft. Luminal surface is completely covered with well-spread and tightly junctioned ECs, beneath which ABM is observed as fibrous collagenous mesh. (Original magnification ×1500.) Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 Scanning electron micrographs of grafts at 2 weeks. (Original magnification A, C and E, ×500; B, ×5000; and D, and F, ×2000.) A and B, Completely endothelialized portion. Endothelial cells are oriented toward blood flow (arrow). C and D, Small thrombi composed of fibrin and adherent platelets are observed at nonendothelialized regions. E and F, Leukocyte migrates into interstices of endothelial cells. Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

4 Fig. 3 Cumulative area frequency distribution of nonendothelialized portions. Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

5 Fig. 4 Percentage of EC coverage as function of implantation period (measured by planimetry). Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

6 Fig. 5 Histologic sections of grafts. (Hematoxylin and eosin stain. Original magnification ×66.) A, Middle portion of graft at 2 weeks. Luminal surface of graft is lined with monolayered ECs, beneath which thinly layered ABM is observed. Artificial basement membrane anchors to micropores of polyurethane graft. B, Middle portion of graft at 4 weeks. Note capillary (arrow) penetrating through polyurethane graft. Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

7 Fig. 6 Histologic sections of graft at 12 weeks. Immunohistochemical stain with muscle-actin-specific antibody identifies that cells observed beneath EC monolayer are SMCs. (A, Original magnification ×128.) Transverse section (B) and longitudinal section (C). (B and C, Hematoxylin and eosin stain. Original magnification ×66.) Difference in cell morphology between two sections demonstrates that circumferential orientation of SMCs is predominant. Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

8 Fig. 7 Histologic section of distal anastomosis at 26 weeks. Luminal surface at anastomosis between artery and graft forms flat and uniform junction. (Hematoxylin and eosin stain. Original magnification ×66.) Journal of Vascular Surgery  , DOI: ( /S (94) ) Copyright © 1994 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

Download ppt "Hiromichi Miwa, MD, Takehisa Matsuda, PhD  Journal of Vascular Surgery "

Similar presentations

Endothelial cell seeding reduces thrombogenicity of Dacron grafts in humans Per Örtenwall, MD, PhD *, Hans Wadenvik, MD, PhD **, Jack Kutti, MD, PhD **,

Endothelial cell seeding reduces thrombogenicity of Dacron grafts in humans Per Örtenwall, MD, PhD *, Hans Wadenvik, MD, PhD **, Jack Kutti, MD, PhD **,
Development and regression of intimal thickening of arterially transplanted autologous vein grafts in dogs  Kazumasa Morinaga, M.D., Hiroshi Eguchi, M.D.,

Development and regression of intimal thickening of arterially transplanted autologous vein grafts in dogs  Kazumasa Morinaga, M.D., Hiroshi Eguchi, M.D.,
Shunya Shindo, M. D. , Atsuhiko Takagi, M. D. , Anthony D

Shunya Shindo, M. D. , Atsuhiko Takagi, M. D. , Anthony D
In vitro endothelialization of a mesosystemic shunt: A clinical case report  Teddy Fischlein, MD, Peter Zilla, MD, PhD, Johann Meinhart, PhD, Rudolf Puschmann,

In vitro endothelialization of a mesosystemic shunt: A clinical case report  Teddy Fischlein, MD, Peter Zilla, MD, PhD, Johann Meinhart, PhD, Rudolf Puschmann,
In vitro tissue engineering of a cardiac graft using a degradable scaffold with an extracellular matrix–like topography  Osamu Ishii, MD, Michael Shin,

In vitro tissue engineering of a cardiac graft using a degradable scaffold with an extracellular matrix–like topography  Osamu Ishii, MD, Michael Shin,
Preliminary experience with tissue engineering of a venous vascular patch by using bone marrow–derived cells and a hybrid biodegradable polymer scaffold 

Preliminary experience with tissue engineering of a venous vascular patch by using bone marrow–derived cells and a hybrid biodegradable polymer scaffold 
Natural history, duplex characteristics, and histopathologic correlation of arterial injuries in a canine model  Thomas F. Panetta, MD, Clifford M. Sales,

Natural history, duplex characteristics, and histopathologic correlation of arterial injuries in a canine model  Thomas F. Panetta, MD, Clifford M. Sales,
Liposuction-derived human fat used for vascular graft sodding contains endothelial cells and not mesothelial cells as the major cell type  Stuart K. Williams,

Liposuction-derived human fat used for vascular graft sodding contains endothelial cells and not mesothelial cells as the major cell type  Stuart K. Williams,
Eddie L. Hoover, M. D. , Margery Ross, Ph. D. , Kazam Fani, M. D

Eddie L. Hoover, M. D. , Margery Ross, Ph. D. , Kazam Fani, M. D
Bioengineered vascular access maintains structural integrity in response to arteriovenous flow and repeated needle puncture  Bryan W. Tillman, MD, PhD,

Bioengineered vascular access maintains structural integrity in response to arteriovenous flow and repeated needle puncture  Bryan W. Tillman, MD, PhD,
Robert J. Pitsch, MD, David J. Minion, MD, Margaret L

Robert J. Pitsch, MD, David J. Minion, MD, Margaret L
Implantation of amniotic membrane as a vascular substitute in the external jugular vein of juvenile sheep  Habibollah Peirovi, MD, Navid Rezvani, MD,

Implantation of amniotic membrane as a vascular substitute in the external jugular vein of juvenile sheep  Habibollah Peirovi, MD, Navid Rezvani, MD,
Gastroesophageal tumor embolization to the popliteal arteries

Gastroesophageal tumor embolization to the popliteal arteries
Central venous catheter failure is induced by injury and can be prevented by stabilizing the catheter tip  Ted R. Kohler, MD, Thomas R. Kirkman, BS  Journal.

Central venous catheter failure is induced by injury and can be prevented by stabilizing the catheter tip  Ted R. Kohler, MD, Thomas R. Kirkman, BS  Journal.
Infection of vascular prostheses caused by bacterial biofilms

Infection of vascular prostheses caused by bacterial biofilms
Vascular anastomoses with laser energy

Vascular anastomoses with laser energy
Development of a “leak-proof,” knitted Dacron vascular prosthesis

Development of a “leak-proof,” knitted Dacron vascular prosthesis
Adenoviral-mediated expression of antisense RNA to basic fibroblast growth factor reduces tangential stress in arterialized vein grafts  Abigail K. Hanna,

Adenoviral-mediated expression of antisense RNA to basic fibroblast growth factor reduces tangential stress in arterialized vein grafts  Abigail K. Hanna,
Lucas P. Neff, MD, Bryan W. Tillman, MD, PhD, Saami K

Lucas P. Neff, MD, Bryan W. Tillman, MD, PhD, Saami K
Preformed confluent endothelial cell monolayers prevent early platelet deposition on vascular prostheses in baboons  Peter A. Schneider, MD, Stephen R.

Preformed confluent endothelial cell monolayers prevent early platelet deposition on vascular prostheses in baboons  Peter A. Schneider, MD, Stephen R.

Similar presentations

Ads by Google