1. Ectomesenchymal odontogenic tumors

2. Odontogenic fibroma

3. Odontogenic fibroma Defenition :-
A fibroblastic odontogenic neoplasm containig varying amount of apparently inactive odontogenic epithelium .

4. Odontogenic fibroma Classification :- A) Intra osseous Who type
Simple type
Granular cell type (now known as granular odontogenic tumor)
B) Extra osseous (peripheral)

5. Odontogenic fibroma
Clinical feature :- -Age: wide range years mean age 40 -sex :female :male 2.2:1 -site common in mandible 55%posterior area 45% in anterior area . Maxilla anterior to first molar -associated with un erupted tooth

7. Odontogenic fibroma
X –ray -unilocular radiolucency (small lesion ) -multilocular radiolucency (large lesion ) -foci of classification (12%)

9. Odontogenic fibroma
Histopathology :- -simple type :- Fibro blast arrange in whorls fine collagen fine fibrils Odontogenic epithelium may or may not present

11. Odontogenic fibroma Who type :-
More cellular fibrous connective tissue with collagen fibers arrange in interlacing bundles, long strands of inactive odontogenic epithelium ,calcifications .

13. Odontogenic fibroma
Treatment :- Vigorous curettage .

14. Benign cementoblastoma

15. Benign cementoblastoma
Defenition :-
A benign ectomesenchymal odontogenic neoplasm that characterized by formation of sheets of cementum like tissue containing a large number of reversal lines.

16. Benign cementoblastoma
Clinical features :- -it’s rare neoplasm . -site :- mandible premolar and molar area specially the first molar 50% . -it’s closely related to and fuse to the root of single tooth . -the involved tooth is vital . -sex :- male predilection .

17. Benign cementoblastoma
X –ray :-
- Radio opacity surround by radiolucent rim .
- Fuse to the root .

18. Benign cementoblastoma
Differential diagnosis (radiographically):- -focal sclerosing osteomylitis :-but it’s associated with non vital tooth it’s not surronded by radio lucent rim . And it ;s not fused to the root in focal sclerosing osteomylitis . -cemento-osseous dysplasias . -osteoma -osteoblastoma. - Osteoid osteoma.

19. Benign cementoblastoma
Histopathology :- -sheets of cementum like tissue containing a large number of reversal lines . -the peripheral part is un mineralized forming radiating columns .

21. Benign cementoblastoma
Treatment :- -surgical removal of mass together with the involved tooth . -surgical endodontic .

22. Odontogenic myxoma

23. Odontogenic myxoma
Defenition It’s a slowly growing locally invasive ectomesenchymal odontogenic tumor Origin It arise from fibroblast or myofibroblast of : 1- dental follicle 2-periodontal ligament

24. Odontogenic myxoma
Clinical feature :- Relative frequency :- the second most common tumor after ameloblastoma It’s slowly growing locally invasive that may be associated with un erupted tooth or displaced and resorbed roots Site :-mandible posterior area Age :-mean age is years Sex no , or female predilection In Sudan it’s found more in male

25. Odontogenic myxoma X-ray :-
multilocular radiolucency soap bubble appearance
Displacement and resorption of adjacent root .
Gross morphology :-
Gelatinous mass .

27. Odontogenic myxoma
Histopathology :- Stellate or spindle shape cells have fibrillar processes lying in mucoid stroma , which contain : -hyaluronic acid and chondritin sulfate -Variable amount of collagen and dense collagen -scattered in active island of odontogenic epithelium .

29. Odontogenic myxoma Differential diagnosis (histopathologically) :-
Non odontogenic myxoma (affect long bone it’s histology similar to odontogenic myxoma but has no inactive odonto genic epithelium ) .
Myxoid variant of neurofibroma .
Chondro-myxoid fibroma .

30. Odontogenic myxoma Treatment : Curettge for small lesions .
Surgical excision for large and maxillary lesions .
Reccurance rate 25%