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Testicular Sperm Retrieval in Azoospermic Men

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Presentation on theme: "Testicular Sperm Retrieval in Azoospermic Men"— Presentation transcript:

1 Testicular Sperm Retrieval in Azoospermic Men
Peter Pantke, Thorsten Diemer, Marcelo Marconi, Martin Bergmann, Klaus Steger, Hans-Christian Schuppe, Wolfgang Weidner  European Urology Supplements  Volume 7, Issue 12, Pages (November 2008) DOI: /j.eursup Copyright © 2008 European Association of Urology Terms and Conditions

2 Fig. 1 (A–F) Different seminiferous tubular histology patterns from TESE samples. Tissues were fixed in Bouin's solution and haematoxylin.eosin stained (A–E) and PLAP antibody haematoxylin stained (F). (A) Seminiferous tubules showing intact spermatogenesis. (B) Seminiferous tubule showing arrest of spermatogenesis at the level of primary pachytene spermatocytes. (C) Seminiferous tubules showing only Sertoli cells (SCO). (D) Different patterns of SCO including hyperplastic Sertoli cells (arrows), and thickening of lamina propria (arrowhead). (E) Total atrophy of seminiferous epithelium leaving only thickened lamina propria (tubular shadows). (F) Seminiferous tubule showing preinvasive testicular intraepithelial neoplasia indicated by the expression of Placental Like Alkaline Phosphatase (PLAP) of atypical germ cells (arrows) next to seminiferous tubule showing intact spermatogenesis. European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions

3 Fig. 2 Incision for TESE following the arterial vascular architecture of the testis indicating a suitable area for sperm extraction according to Schroeder-Printzen (thesis – University of Giessen). European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions

4 Fig. 3 Probability of pregnancy with regard to hypospermatogenesis as determined by the percentage of testicular tubules containing elongated spermatids in testicular sperm extraction samples (modified from [41]). European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions

5 Fig. 4 Current approach to azoospermic patients.
OA=obstructive azoospermia; NOA=nonobstructive azoospermia; TESE=testicular sperm extraction; M-TESE=microscopic testicular sperm extraction. European Urology Supplements 2008 7, DOI: ( /j.eursup ) Copyright © 2008 European Association of Urology Terms and Conditions


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