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Expression of myosin heavy chain isoforms in skeletal muscle of patients with peripheral arterial occlusive disease  Jürgen M. Steinacker, MD, Alexandra.

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Presentation on theme: "Expression of myosin heavy chain isoforms in skeletal muscle of patients with peripheral arterial occlusive disease  Jürgen M. Steinacker, MD, Alexandra."— Presentation transcript:

1 Expression of myosin heavy chain isoforms in skeletal muscle of patients with peripheral arterial occlusive disease  Jürgen M. Steinacker, MD, Alexandra Opitz-Gress, MD, Susanne Baur, MD, Werner Lormes, PhD, Klaus Bolkart, MA, Ludger Sunder- Plassmann, MD, Florian Liewald, MD, Manfred Lehmann, MD, Yuefei Liu, MD  Journal of Vascular Surgery  Volume 31, Issue 3, Pages (March 2000) DOI: /mva Copyright © 2000 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

2 Fig. 1 An example of MHC isoforms analyzed by SDS-PAGE. Lanes 1 through 4 represent muscle samples from a control patient and from patients with PAOD II, III and IV, respectively. Each protein band was measured densitometrically and expressed as a percentage, taking all bands of a sample as 100%. Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2000 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

3 Fig. 2 MHC isoform distribution between control patients and patients with PAOD with clinical stage II, III, IV. In comparison with control patients, there was no change of MHC isoforms in patients with PAOD II, but there was a significant decrease of MHC IIb in PAOD III and IIa and of IIb in PAOD IV. Journal of Vascular Surgery  , DOI: ( /mva ) Copyright © 2000 Society for Vascular Surgery and International Society for Cardiovascular Surgery, North American Chapter Terms and Conditions

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