1. Quantile-Quantile plot
Manhattan plot of HDL cholesterol GWAS
Genome-wide significance
(p-value = 5 x 10-8)
Suggestive association
(p-value = 1 x 10-5)
-log10(p-value)
Chromosome
Quantile-Quantile plot
Genomic inflation (λ) =
Observed –log10(P)
Expected –log10(P)
Supplementary Figure S1. Manhattan and quantile-quantile plot for CAVAS GWAS results of HDL cholesterols

2. Quantile-Quantile plot
Manhattan plot of LDL cholesterol GWAS
Genome-wide significance
(p-value = 5 x 10-8)
Suggestive association
(p-value = 1 x 10-5)
-log10(p-value)
Chromosome
Quantile-Quantile plot
Genomic inflation (λ) =
Observed –log10(P)
Expected –log10(P)
Supplementary Figure S2. Manhattan and quantile-quantile plot for CAVAS GWAS results of LDL cholesterols

3. Quantile-Quantile plot
Manhattan plot of Triglycerides GWAS
Genome-wide significance
(p-value = 5 x 10-8)
Suggestive association
(p-value = 1 x 10-5)
-log10(p-value)
Chromosome
Quantile-Quantile plot
Genomic inflation (λ) =
Observed –log10(P)
Expected –log10(P)
Supplementary Figure S3. Manhattan and quantile-quantile plot for CAVAS GWAS results of Triglycerides

4. Quantile-Quantile plot
Manhattan plot of total cholesterols GWAS
Genome-wide significance
(p-value = 5 x 10-8)
Suggestive association
(p-value = 1 x 10-5)
-log10(p-value)
Chromosome
Quantile-Quantile plot
Genomic inflation (λ) =
Observed –log10(P)
Expected –log10(P)
Supplementary Figure S4. Manhattan and quantile-quantile plot for CAVAS GWAS results of Total cholesterols

5. Supplementary Figure S5
Supplementary Figure S5. Principal Component Analysis plots for CAVAS (Red), KARE (Blue), and HEXA (Yellow) with HAPMAP populations (Purple).