1. Volume 11, Issue 4, Pages 201-208 (May 2005)
Reduced LPA expression after peroxisome proliferator-activated receptor alpha (PPARα) activation in LPA-YAC transgenic mice 
Päivi A. Teivainen-Laedre, Knut A. Eliassen, Marit Sletten, Adrian J. Smith, Kåre Berg 
Pathophysiology 
Volume 11, Issue 4, Pages (May 2005)
DOI: /j.pathophys
Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

2. Fig. 1
Effect of 3 weeks feeding of fenofibrate (FF) or WY (WY) supplemented diet on serum apo(a) levels in LPA transgenic mice with or without the LPA–PLG intergenic region. Apo(a) levels in individual mouse serum were measured using a commercially available RIA kit. Data are presented as mean±S.E.M. (mg/dl). Number of mice is presented in parentheses. Black bars represent serum apo(a) levels at the start and open bars represent levels after 3 weeks feeding of control, FF or WY supplemented diet. The asterisk (*P<0.05) and double asterisk (**P<0.005) indicate statistically significant differences compared to respective mice fed the control diet. FF: 0.1% (w/w) fenofibrate supplemented diet; WY 14643: 0.05% (w/w) WY supplemented diet.
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

3. Fig. 2
Effect of 3 weeks feeding of fenofibrate (FF) or WY (WY) supplemented diet on hepatic apo(a) mRNA levels in LPA transgenic mice with or without the LPA–PLG intergenic region. For normalization of expression data means of cyclophilin and β-actin mRNA level were used. Data are presented as the mean±S.E.M. of normalized expression levels. Number of mice is presented in parentheses. Open bars represent mice on the control diet. Grey or black bars represent levels in mice fed the FF or WY supplemented diet, respectively. The asterisk (*P<0.05) and double asterisk (**P<0.005) indicate statistically significant differences compared to respective mice fed the control diet. FF: 0.1% (w/w) fenofibrate supplemented diet; WY 14643: 0.05% (w/w) WY supplemented diet.
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

4. Fig. 3
Hepatic CY7A1 mRNA levels in WT or LPA-YAC transgenic mice fed control diet or diets supplemented with fenofibrate (FF) or WY (WY) for 3 weeks. For normalization of expression data means of cyclophilin and β-actin mRNA level were used. Data is presented as mean±S.E.M. of normalized expression levels. Number of mice is presented in parentheses. Open bar represents median levels in mice fed the control diet. Grey and black bars represent median levels in mice fed the FF or the WY supplemented diet, respectively. The asterisk (*P<0.05) indicates a statistically significant difference compared to the respective control group. WT: wild type; FF: 0.1% (w/w) fenofibrate supplemented diet; WY 14643: 0.05% (w/w) WY supplemented diet.
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

5. Fig. 4
Hepatic FXR mRNA level in WT and LPA-YAC transgenic mice fed a control diet or diets supplemented with fenofibrate (FF) or WY (WY) for 3 weeks. For normalization of expression data means of cyclophilin and β-actin mRNA level were used. Data are presented as mean±S.E.M. of normalized expression levels. Open bars represent median values in mice fed the control diet. Grey and black bars represent FF or WY treated mice, respectively. The asterisk (*P<0.05) and double asterisk (**P<0.005) indicate statistically significant differences compared to the respective control group. FF: 0.1% (w/w) supplemented fenofibrate diet; WY 14643: 0.05% (w/w) WY supplemented diet.
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

6. Fig. 5
Hepatic LXR mRNA level in WT and LPA-YAC transgenic mice fed a control diet or diets supplemented with fenofibrate (FF) or WY (WY) for 3 weeks. For normalization of expression data means of cyclophilin and β-actin mRNA level were used. Data is presented as mean±S.E.M. of normalized expression levels. Open bars represent median values in mice fed the control diet. Grey and black bars represent FF or WY treated mice, respectively. The asterisk (*P<0.05) indicates statistically significant difference compared to the respective control group. FF: 0.1% (w/w) supplemented fenofibrate diet; WY 14643: 0.05% (w/w) WY supplemented diet.
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

7. Fig. 6
Hepatic APO A5 mRNA level in WT and LPA-YAC transgenic mice fed a control diet or diets supplemented with fenofibrate (FF) or WY (WY) for 3 weeks. For normalization of expression data means of cyclophilin and β-actin mRNA level were used. Data is presented as mean±S.E.M. of normalized expression levels. Open bars represent median values in mice fed the control diet. Grey and black bars represent FF or WY treated mice, respectively. FF: 0.1% (w/w) supplemented fenofibrate diet; WY 14643: 0.05% (w/w) WY supplemented diet.
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions