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Volume 11, Issue 2, Pages (October 2004)

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Presentation on theme: "Volume 11, Issue 2, Pages (October 2004)"— Presentation transcript:

1 Volume 11, Issue 2, Pages 113-120 (October 2004)
Atherogenesis and vascular calcification in mice expressing the human LPA gene  Päivi A. Teivainen, Knut A. Eliassen, Kåre Berg, Kari Torsdalen, Aud Svindland  Pathophysiology  Volume 11, Issue 2, Pages (October 2004) DOI: /j.pathophys Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

2 Fig. 1 Photomicrograph showing two aortic lesions in aortic root near cusps in female LPA-YAC/hAPOB transgenic mouse fed on the HC diet for 7 weeks. Figure shows a section with two separate plaques of fatty streak type (original magnification 100×). These plaques are presented with original magnification 400× in cuts (A) and (B). In cut (A) a lesion with accumulation of extracellular lipids and a single foam cell (arrow) on the endothelial surface is seen. In cut (B) a aortic lesion with calcification (arrows) is seen. Pathophysiology  , DOI: ( /j.pathophys ) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions

3 Fig. 2 Normalized hepatic apo(a) mRNA levels in female LPA-YAC and LPA-YAC/hAPOB transgenic mice fed three different diets for 7 weeks. HC: high-cholesterol diet, HCHF: high-cholesterol/high-fat diet. Pathophysiology  , DOI: ( /j.pathophys ) Copyright © 2004 Elsevier Ireland Ltd Terms and Conditions


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