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Preclinical investigation of the development of osteoarthritis-like degeneration in a rat trauma model using micro-computed tomography  T.H. Steiner,

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Presentation on theme: "Preclinical investigation of the development of osteoarthritis-like degeneration in a rat trauma model using micro-computed tomography  T.H. Steiner,"— Presentation transcript:

1 Preclinical investigation of the development of osteoarthritis-like degeneration in a rat trauma model using micro-computed tomography  T.H. Steiner, R.J. Choo, A. Quintin, M. Wilke, D. Nesic, M. Zulliger, R. Müller, K.S. Stok  Osteoarthritis and Cartilage  Volume 20, Pages S50-S51 (April 2012) DOI: /j.joca Copyright © Terms and Conditions

2 Figure 1 Sagittal cut through a knee joint with microCT and contrast agent. F: femur, T: tibia, CA: contrast agent, M: meniscus, Cg: cartilage. Osteoarthritis and Cartilage  , S50-S51DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Figure 2 (a) 2D Cg.Th of histology and microCT slice for healthy and OA-induced rat knees (p < 0.001). (b-c) 3D thickness maps of tibial cartilage for the two models. Osteoarthritis and Cartilage  , S50-S51DOI: ( /j.joca ) Copyright © Terms and Conditions

4 Figure 3 OA-induced tibio-femoral rat joint in coronal plane with bone (white) and cartilage (colour indicates thickness) allowing direct investigation of local bone adaptation with cartilage changes. Osteoarthritis and Cartilage  , S50-S51DOI: ( /j.joca ) Copyright © Terms and Conditions

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