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University of Windsor Animal User Training Program
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Gwendolyn Jeun, D.V.M. Honours Bachelor of Science, Zoology (UWO)
Master of Science, Zoology (UWO) Doctor of Veterinary Medicine (Ontario Veterinary College, U of Guelph) Aquavet, Woods Hole Mystic Marinelife Aquarium, Connecticut
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Legislation and Regulation
Canadian Council on Animal Care OMAFRA - “Animals for Research Act” University of Windsor Animal Care Committee Ministry of Natural Resources etc. for fieldwork and wildlife
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Canadian Council on Animal Care (CCAC)
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Canadian Council on Animal Care (CCAC)
The Three Rs Reduction Refinement Replacement
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The Three R’s www.altweb.jhsph.edu Center for Alternatives to
Animal Testing at Johns Hopkins University -to foster development of scientifically acceptable in vitro & other R-R-R alternatives for animal testing
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Replacement are there appropriate alternatives?
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Refinement achieve expertise limit pain prevent wasting of animals
expertise can reduce variability thus reducing numbers required
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Reduction appropriate animal numbers - statistical requirements
controlling variability literature researches
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CCAC How does CCAC accomplish its goals? 3 Rs Guidelines Assessment
Education
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CCAC Guidelines “Guide to the Care and Use of Experimental Animals, Volumes 1 & 2” Vol 1 - principles for good animal care and use Vol 2 - husbandry of experimental animals on a species by species basis Available through
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Assessment CCAC assessment panel carries out site visits to ensure guidelines are being followed status of compliance, conditional compliance or non-compliance if non-compliant, CCAC can inform granting agencies (e.g. NSERC)
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Education via CCAC assessment panel
CCAC workshops for members of Animal Care Committee National Institutional Animal User Training Program (NIAUT) - ensures all personnel are trained in basic principles of lab animal science and ethical issues
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Ontario Ministry of Agriculture Food and Rural Affairs (OMAFRA)
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Animals for Research Act
provincial legislation protecting all animals used in research and testing applies to all vertebrates - fish, rodents, reptiles, birds, primates and livestock OMAFRA responsible for administering and enforcing the law
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Required by law Animal Care Committee at U of W
Research Proposals or Protocols
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Objectives of the Act maintain a minimum standard of care
protect research animals from unnecessary pain assure that dogs and cats used for research are obtained legally
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Key elements of the Act minimum standards of housing and care
animal care committees research proposals veterinary inspectors dog pounds and supply facilities pet protection
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Housing and Care cage size, construction, cleanliness
food, water and bedding ventilation, temperature, humidity transportation of animals surgical facilities and procedures must meet established veterinary standards
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Protocols must be submitted well before animal use is to begin so ACC can review: -suitable animal numbers - appropriate species - appropriate procedures - unnecessary pain/discomfort - scientific work
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Veterinary Inspectors
unannounced visits authority to enter any area where they believe animal research is taking place inspect all aspects of animal use to ensure it meets the requirements of the Act can revoke registration of research facility and lay court charges
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U of W Animal Care Committee (ACC)
required by both CCAC and “Animals for Research Act” ensures that all animal use meets guidelines accomplished via: research and teaching protocols training and information sessions veterinary inspections
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ACC Members Vice President Research
representative from each user department non-animal user from University community lay person veterinarian student representative others as needed
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Animal Facilities Great Lakes Institute Biology Psychology
Human Kinetics (not active currently)
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Wildlife and Fieldwork
all the same rules and regulations apply, PLUS additional laws and permits Migratory Birds Convention Act Game Export Act provincial Fish and Wildlife Acts Convention on International Trade in Endangered Species (CITES)
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