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Commentary: Rejuvenation of “broken heart” with bioengineered gel

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1 Commentary: Rejuvenation of “broken heart” with bioengineered gel
Devendra K. Agrawal, PhD, MBA, Aleem Siddique, MBBS  The Journal of Thoracic and Cardiovascular Surgery  Volume 157, Issue 4, Pages (April 2019) DOI: /j.jtcvs Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

2 Figure 1 Schematic diagram showing the direct participation of endothelial progenitor cells (EPCs) to induce angiogenesis and the paracrine effect of shear-thinning hydrogel (STG) containing endothelial progenitor cells to increase retention, proliferation, migration, and differentiation of progenitor cells in the infarct zone, resulting in increased left ventricular (LV) ejection fraction and contractility and thus inducing protective and regenerative effects on cardiomyocytes. HA, Hyaluronic acid; ECM, extracellular matrix. The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions

3 Devendra K. Agrawal, PhD, MBA (left), and Aleem Siddique, MBBS (right)
The Journal of Thoracic and Cardiovascular Surgery  , DOI: ( /j.jtcvs ) Copyright © 2018 The American Association for Thoracic Surgery Terms and Conditions


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