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Y. Zhou, L. Resutek, L. Wang, X. Lu  Osteoarthritis and Cartilage 

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Presentation on theme: "Y. Zhou, L. Resutek, L. Wang, X. Lu  Osteoarthritis and Cartilage "— Presentation transcript:

1 In situ calcium signaling of chondrocytes under serum-free and serum culture 
Y. Zhou, L. Resutek, L. Wang, X. Lu  Osteoarthritis and Cartilage  Volume 21, Pages S124-S125 (April 2013) DOI: /j.joca Copyright © Terms and Conditions

2 Fig. 1 (A) Cartilage explant on the confocal microscope; (B) A fluorescent image of chondrocytes in cartilage explant. Osteoarthritis and Cartilage  , S124-S125DOI: ( /j.joca ) Copyright © Terms and Conditions

3 Fig. 2 Comparison of [Ca2+]i responses between serum and serum-free group (serum-free group: 4068 cells, serum group: 3444 cells). (A) Responsive percentage of cells; (B) Number of peaks of responsive cells. (*: p<0.05, between the two groups). Osteoarthritis and Cartilage  , S124-S125DOI: ( /j.joca ) Copyright © Terms and Conditions

4 Fig. 3 Comparison of spatiotemporal properties of [Ca2+]i responses. (A) Magnitude of all peaks for each cell (arbitrary unit); (B) Time to reach a calcium peak; (C) Peak relaxation time; (D) Time interval between two peaks. (*: p<0.05, between the two groups). Osteoarthritis and Cartilage  , S124-S125DOI: ( /j.joca ) Copyright © Terms and Conditions

5 Fig. 4 Dynamic modulus of cartilage in serum and serum-free group (n=12). (*: p<0.05, between the two groups). Osteoarthritis and Cartilage  , S124-S125DOI: ( /j.joca ) Copyright © Terms and Conditions


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