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Martha D. McDaniel, M. D. , William H. Pearce, M. D. , James S. T

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Presentation on theme: "Martha D. McDaniel, M. D. , William H. Pearce, M. D. , James S. T"— Presentation transcript:

1 Sequential changes in coagulation and platelet function following femorotibial bypass 
Martha D. McDaniel, M.D., William H. Pearce, M.D., James S.T. Yao, M.D., Ennio C. Rossi, M.D., Victora A. Fahey, B.S.N., David Green, M.D., William R. Flinn, M.D., John J. Bergan, M.D.  Journal of Vascular Surgery  Volume 1, Issue 2, Pages (March 1984) DOI: / (84) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

2 Fig. 1 Platelet reactivity to collagen in 24 patients before and after femorotibial bypass graft placement. A, Distribution of Kd values before surgery and 3 and 7 days after surgery (shaded area = normal range). B, Mean values ± SEM for each set of observations. There was a significant decrease in platelet reactivity on postoperative day 3 (p < 0.001). Journal of Vascular Surgery 1984 1, DOI: ( / (84) ) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

3 Fig. 2 Factor VIII—related antigen in 23 patients before and after femorotibial bypass graft placement. A, Factor VIII—related antigen was elevated in 17 patients (shaded area = normal range). B, Mean values ± SEM for each set of observations. There was a significant increase in factor VIII—related antigen on third and seventh postoperative days (p < 0.01). Journal of Vascular Surgery 1984 1, DOI: ( / (84) ) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions

4 Fig. 3 Antithrombin III plasma levels in 14 patients who received no antiplatelet medications before and after femorotibial bypass graft placement. A, Observed values in 14 patients before and 3 and 7 days after surgery (shaded area = normal range). B, Mean values ± SEM for each set of observations. There was a significant decrease in antithrombin III on third postoperative day. Journal of Vascular Surgery 1984 1, DOI: ( / (84) ) Copyright © 1984 Society for Vascular Surgery and North American Chapter, International Society for Cardiovascular Surgery Terms and Conditions


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