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Tyr105 to Cys105 point mutation in human ZC3H10 is associated with altered metabolic phenotype Tyr105 to Cys105 point mutation in human ZC3H10 is associated.

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Presentation on theme: "Tyr105 to Cys105 point mutation in human ZC3H10 is associated with altered metabolic phenotype Tyr105 to Cys105 point mutation in human ZC3H10 is associated."— Presentation transcript:

1 Tyr105 to Cys105 point mutation in human ZC3H10 is associated with altered metabolic phenotype
Tyr105 to Cys105 point mutation in human ZC3H10 is associated with altered metabolic phenotype Genome browser representation of Hg38 ZC3H10 locus (upper part) and sequence of the tyrosine 105 (red) neighborhood in ZC3H10 coding sequence (lower part).Body mass index (BMI), waist circumference, total fat mass, waist/hip ratio, fasting glucose and triglyceride (TG) in Tyr105 (black), Tyr105Cys (red), and Cys105 (blue) subjects. Tyr105, n = 697. Tyr105Cys, n = Cys, n = 4. Data are expressed as mean ± SD for BMI, waist circumference, total fat mass, and waist/hip ratio. For fasting glucose and TG, data are expressed as median ± interquartile range (Tyr105 and Tyr105 Cys) and mean ± SD for Cys105. Statistical analysis was performed by Kruskal–Wallis (Dunn's post hoc analysis). *P < 0.05 vs. Tyr105 and #P < 0.05 vs. Tyr105Cys. Matteo Audano et al. EMBO Rep. 2018;19:e45531 © as stated in the article, figure or figure legend

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