1. Altered Serum n-6 Polyunsaturated Fatty Acid Profile and Risks of Mortality and Cardiovascular Events in a Cohort of Hemodialysis Patients 
Yukinobu Kuwamura, MD, Tetsuo Shoji, MD, PhD, Yujiro Okute, MD, PhD, Yuko Yamazaki, MD, PhD, Koka Motoyama, MD, PhD, Tomoaki Morioka, MD, PhD, Katsuhito Mori, MD, PhD, Shinya Fukumoto, MD, PhD, Yoshihiro Tsujimoto, MD, PhD, Atsushi Shioi, MD, PhD, Masanori Emoto, MD, PhD, Masaaki Inaba, MD, PhD 
Journal of Renal Nutrition 
Volume 28, Issue 1, Pages (January 2018)
DOI: /j.jrn
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

2. Figure 1
Comparison of DGLA, AA, and D5D index between hemodialysis and control groups. Box plots indicate 10th, 25th, 50th, 75th, and 90th percentile levels. P values are by Mann–Whitney U-test. DGLA, dihomo-γ-linoleic acid; AA, arachidonic acid; D5D index, δ5-desaturase index defined by AA/DGLA ratio.
Journal of Renal Nutrition  , 54-63DOI: ( /j.jrn )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

3. Figure 2
Kaplan–Meier curves for D5D index quartile and risks of all-cause mortality, CVD events, and composite of the 2. D5D, δ5-desaturase index; CVD, cardiovascular disease; Q, quartile.
Journal of Renal Nutrition  , 54-63DOI: ( /j.jrn )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions

4. Figure 3
Adjusted associations of D5D index with various outcomes in hemodialysis patients including and excluding statin users. The graphs indicate hazard ratios and 95% confidence intervals. The model was adjusted for age, sex, duration on hemodialysis, diabetic nephropathy, pre-existing CVD, and (EPA + DHA)/AA ratio. EPA, eicosapentaenoic acid; DHA, docosahexaenoic acid; DGLA, dihomo-γ-linoleic acid; AA, arachidonic acid; D5D index, δ5-desaturase index defined by AA/DGLA ratio; Q, quartile; CVD, cardiovascular disease.
Journal of Renal Nutrition  , 54-63DOI: ( /j.jrn )
Copyright © 2017 National Kidney Foundation, Inc. Terms and Conditions