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Translation © 2016 Paul Billiet ODWS.

Published byἜρεβος Κοτζιάς Modified over 5 years ago

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Presentation on theme: "Translation © 2016 Paul Billiet ODWS."— Presentation transcript:

1 Translation © 2016 Paul Billiet ODWS

2 Translation plan Complete protein Polypeptide chain TRANSLATION
Ribosomes Stop codon Start codon © 2016 Paul Billiet ODWS

3 Translation1 Ribosome AUGGGAUACACUUUUUGA mRNA © 2016 Paul Billiet ODWS

4 Translation 2 met UAC tRNA amino acid anticodon
tRNA binding sites & functions: A entry P peptide bond formation E exit P site AUGGGAUACACUUUUUGA © 2016 Paul Billiet ODWS

5 Translation 3 CCU UAC gly met AUGGGAUACACUUUUUGA A site
© 2016 Paul Billiet ODWS

6 Translation 4 peptide bond CCU UAC gly met AUGGGAUACACUUUUUGA
© 2016 Paul Billiet ODWS

7 Translation 5 UAC CCU AUG tyr gly met AUGGGAUACACUUUUUGA E site
© 2016 Paul Billiet ODWS

8 Translation 6 CCU AUG gly met tyr AUGGGAUACACUUUUUGA
© 2016 Paul Billiet ODWS

9 Translation 7 UGA thr CCU AUG gly met tyr AUGGGAUACACUUUUUGA
© 2016 Paul Billiet ODWS

10 Translation 8 AAA phe polypeptide chain UGA gly met tyr thr AUG
AUGGGAUACACUUUUUGA © 2016 Paul Billiet ODWS

11 Translation: the sequence
The tRNA molecules with the correct anticodons line up with bases complementary to the mRNA codons Three tRNA molecules at a time can fit on the ribosome (at three sites A, P and E) A peptide bond forms between the first two amino acids on the first two tRNA (at P site) The first tRNA leaves the ribosome (at E site) and mRNA move along to accept a new tRNA (at A site) The process of translation proceeds in the same direction as replication and transcription (5’ to 3’). © 2016 Paul Billiet ODWS

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