1. Regulation of oligodendrocyte differentiation: Insights and approaches for the management of neurodegenerative disease 
Abdullah Mohammad Tauheed, Joseph Olusegun Ayo, Mohammed Umaru Kawu 
Pathophysiology 
Volume 23, Issue 3, Pages (September 2016)
DOI: /j.pathophys
Copyright © 2016 Elsevier B.V. Terms and Conditions

2. Fig. 1
Schematic representation of interplay among prominent factors in the intrinsic and extrinsic pathways of oligodendrocyte differentiation.
A: Oligodendrocyte progenitor cells (OPCs) differentiate to myelinate axon. B: Contact of differentiating oligodendrocyte with axon elicits contact inhibition of further myelination by the differentiating oligodendrocytes. This contact inhibition is mediated by Id4 in the intrinsic pathway and Wnt/β-catenin in the extrinsic pathway. C: Histone deacetylase (HDAC) simultaneously eliminates inhibitory effects of Id4 and Wnt/β-catenin in B and allows for myelination to progress.
Pathophysiology  , DOI: ( /j.pathophys )
Copyright © 2016 Elsevier B.V. Terms and Conditions