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Distinct TF motifs are associated with decreased or increased H3K27 acetylation peaks in hypothyroidism. Distinct TF motifs are associated with decreased.

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Presentation on theme: "Distinct TF motifs are associated with decreased or increased H3K27 acetylation peaks in hypothyroidism. Distinct TF motifs are associated with decreased."— Presentation transcript:

1 Distinct TF motifs are associated with decreased or increased H3K27 acetylation peaks in hypothyroidism. Distinct TF motifs are associated with decreased or increased H3K27 acetylation peaks in hypothyroidism. (A) The JASPER database was used to identify TF motifs that were contained within H3K27 acetylation peaks that were down-regulated (left column) or up-regulated (right column) in WT mice in the hypothyroid condition. (The heat map was generated in (B) Scored percentage of the co-occurrence (CO) of TF motifs with TRβ1 motifs that have either up-regulated or down-regulated H3K27 acetylation peaks in hypothyroidism. Arturo Mendoza et al. PNAS 2017;114:40:E8458-E8467 ©2017 by National Academy of Sciences

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