Presentation is loading. Please wait.

Presentation is loading. Please wait.

Obidallah Aljaghthmi, Isam Abu Zeid, Hassan Heba, Sherif Hassan

Similar presentations


Presentation on theme: "Obidallah Aljaghthmi, Isam Abu Zeid, Hassan Heba, Sherif Hassan"— Presentation transcript:

1 Obidallah Aljaghthmi, Isam Abu Zeid, Hassan Heba, Sherif Hassan
Histological difference of Soleus Muscle fibers due to Sciatic Nerve Transection in Rats  Obidallah Aljaghthmi, Isam Abu Zeid, Hassan Heba, Sherif Hassan  Pathophysiology  DOI: /j.pathophys Copyright © Terms and Conditions

2 Fig. 1 A light photomicrograph showing a longitudinal section of the soleus muscle of control rat. The section shows normal longitudinally arranged parallel muscle fibers (mf) enclosed by a thin sheath of the perimysium (P).The muscle fibers are multinucleated and the nuclei (N) are flattened and peripherally located(H& E Stain). Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

3 Fig. 2 A light photomicrograph of a longitudinal muscle section of control soleus showing the normal transverse (arrow head) and longitudinal striations of the muscle fibers (mf).A thin perimysium connective tissue layer (P) surrounds a group of muscle fibers (mf).N: nucleus (H& E). Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

4 Fig. 3 A light photomicrograph of a longitudinal section of control soleus muscle showing a thin layer of perimysium (P) enclosing a group of muscle fibers (mf).The perimysium contains little amount of collagen fibers.The muscle fibers have longitudinal and transverse (arrow head) striations.Masson’s Trichrome stain. Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

5 Fig. 4 A light micrograph of the rat soleus muscle two weeks post-transection of the sciatic nerve showing reduction in the diameter of the muscle bundles (mf) with wavy arrangment, loss of the transverse striations (*) and deeply positioned nuclei (N).Extensive inflammatory cell infiltration is seen around the affected areas (I).Wide perimysium (P) is seen between the muscle bundles.(H & E). Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

6 Fig. 5 A light micrograph of the rat soleus muscle two weeks post-transection of the sciatic nerve showing marked reduction in the thickness of the myofilaments (*) of the degenerated area(D). Note the wide perimysium (P) in-between the bundles of myofilaments (mf). I: inflammatory cell infiltration; BV: blood vessel(H & E). Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

7 Fig. 6 A light micrograph of the rat soleus muscle two weeks post-transection of the sciatic nerve showing minimal fibrous tissues (*) of the perimysium (P) between the muscle fibers (mf).Masson’s Trichrome Stain. Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

8 Fig. 7 A light micrograph of the rat soleus muscle four weeks post-transection of the sciatic nerve showing wide areas of degeneration (D) with inflammatory cell infiltration (I) and wide perimysium (P). Fig. 7B shows a congested thick walled artery (A) and inflammatory cell infiltration (I).(H & E). Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

9 Fig. 8 A light micrograph of the rat soleus muscle four week post-transection of the sciatic nerve showing excessive amount of the fibrous tissues (*) within the degenerated area (D) of muscle and within the wide perimysium (P) between the muscle fibers (mf). Masson’sTrichrome Stain. Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

10 Fig. 9 A light micrograph of a rat soleus muscle eight weeks post-transection of the sciatic nerve showing wide perimysium (P) on each side of the bundle of the myofibers (mf).Loss of the transverse striations and wavy arrangement of the myofibers (mf) are seen (Fig. 9A).The degenerated area (D) contains homogenous collagenous substances (*) and minimal inflammatory cells infiltration (I).A few nuclei (N) show central position (Fig. 9B) (H & E). Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions

11 Fig. 10 A light micrograph of a rat soleus muscle eight weeks post-transection of the sciatic nerve showing little amount of collagen fibers (*) within the thin perimysium (P).The myofibers (mf) have wavy appearance.Masson’sTrichromestain Pathophysiology DOI: ( /j.pathophys ) Copyright © Terms and Conditions


Download ppt "Obidallah Aljaghthmi, Isam Abu Zeid, Hassan Heba, Sherif Hassan"

Similar presentations


Ads by Google