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Uremic pruritus Kidney International
Thomas Mettang, Andreas E. Kremer Kidney International Volume 87, Issue 4, Pages (April 2015) DOI: /ki Copyright © 2015 International Society of Nephrology Terms and Conditions
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Figure 1 Typical skin changes observed in patients suffering from chronic kidney disease-associated pruritus (CKD-aP). (a) Scratch marks with excoriations at the lower leg. (b) Typical hyperkeratotic partly excoriated nodules (prurigo nodularis) located on the forearm. (c) Deep scars and prurigo nodules at the shoulders and back of a female patient. Kidney International , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions
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Figure 2 Prevalence and intensity of uremic pruritus according to DOPPS-data from 1996 to 1999 (I) and 2002 to 2003 (II) (after Pisoni et al.1). DOPPS, Dialysis Outcome and Practice Patterns Study. Kidney International , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions
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Figure 3 Prevalence of uremic pruritus in children on dialysis (18 years or younger) and in adult dialysis patients (older than 18 years). Prevalence of uremic pruritus in children is significantly lower than in adult patients (χ2 test according to Schwab et al.13). Kidney International , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions
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Figure 4 Schematic synopsis of potential pathogenic factors in chronic kidney disease-associated pruritus (CKD-aP). CNS, central nervous system. Kidney International , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions
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Figure 5 Therapeutic algorithm in chronic kidney disease-associated pruritus (CKD-aP). Kt/V, urea clearance in relation to urea distribution volume; UVB, ultraviolet light B. Kidney International , DOI: ( /ki ) Copyright © 2015 International Society of Nephrology Terms and Conditions
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