1. High-flow Nasal Cannula
Prepared by Shane Barclay MD

2. Objectives Define High Flow Nasal Cannula system.
Review the indication of HFNC in a rural setting.
Review the contraindications and complications of HFNC.
Cover the actual set up and use of a HFNC system.

3. High flow nasal cannula - HFNC
Definition: System providing heated and humidified oxygen delivered up to an FiO2 100% and flow rates up to 60 – 70 liter per minute.

4. HFNC - indications
HFNC has various applications. Those listed below could be applicable in a rural hospital setting.
Hypoxic Respiratory Failure.
- pneumonia, pulmonary edema, CO poisoning, acute asthma, PE.
2. Pre-intubation oxygenation.
3. Palliative (do not intubate) scenarios.
Historically used in pediatrics, but now increasingly in adults.

5. HFNC - contraindications
Epistaxis.
Recent nasal surgery.
Known nasal obstruction.
Basilar skull fracture.

6. HFNC -complications Epistaxis. Gastric distention.
Local discomfort and pressure areas.
Excessive PEEP in newborns (causing pneumothorax).
Delayed intubation while ‘hoping’ HFNC will correct things.

7. HFNC – actual systems
There are several commercial products available. This presentation will cover the Airvo 2 system. The simplest way to demonstrate are the 4 videos showing Airvo 2 on the accompanying web page. Each is about 6 – 8 minutes long.

8. HFNC – some other information
CPAP – HFNC have been shown to generate some degree of PEEP if the patient keeps their mouth closed. PEEP can be in the range up to 5 – 7 cm H2O when using 60 lpm.
Patients report it is much more comfortable than ‘dry air’ ie NRB, prongs etc.
Disadvantage is that it is harder to set up than prongs or NRB.

9. HFNC – does it work?
Oddly enough the jury is still out on a complete answer. There are several contradictory studies for acute respiratory failure and for pre-oxygenation for intubation. For now, HFNC is worth using for acute or pending respiratory failure, especially in children. For RSI pre-oxygenation, if it can be set up quickly, it would seem a reasonable option as there is positive research in this area.

10. HFNC – does it work?
A quick note on nasal prongs versus HFNC for pre-oxygenation.
If you put on nasal prongs, then turn the regulator up to 15 lpm and then continue to turn the knob to maxiumum, you can actually get up to 40 – 60 lpm flow from the wall.
You can put that through a regular nasal cannula before and during intubation and still achieve high flow oxygen that may assist in apneic oxygenation.
Although this is ‘dry air’, used for short term is not detrimental to the patient.
It is also much faster to set up than HFNC.

11. THE END