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William J. Hogan, MB, MRCPI, Robert D. McBane, MD, Paula J

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1 Antiphospholipid Syndrome and Perioperative Hemostatic Management of Cardiac Valvular Surgery 
William J. Hogan, MB, MRCPI, Robert D. McBane, MD, Paula J. Santrach, MD, Elizabeth A. Plumhoff, MT(ASCP), William C. Oliver, MD, Hartzell V. Schaff, MD, Richard J. Rodeheffer, MD, William D. Edwards, MD, Joseph Duffy, MD, William L. Nichols, MD  Mayo Clinic Proceedings  Volume 75, Issue 9, Pages (September 2000) DOI: / Copyright © 2000 Mayo Foundation for Medical Education and Research Terms and Conditions

2 Figure 1 Gross photograph of resected aortic valve, showing aortic aspect. Aortic valve has 3 distinct cusps, with moderate to marked fibrosis and cusp retraction, without annular dilation, with an apparent fixed triangular central orifice. Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2000 Mayo Foundation for Medical Education and Research Terms and Conditions

3 Figure 2 Resected aortic valve cusps. Left, Nodular thickening of the distal half of the cusp (chronic noncalcified fibrosis) with microfocal thrombus (arrow) (hematoxylin-eosin, original magnification x12). Right, Organizing thrombotic vegetation characteristic of primary antiphospholipid antibody syndrome (hematoxylin-eosin, original magnification x120). Mayo Clinic Proceedings  , DOI: ( / ) Copyright © 2000 Mayo Foundation for Medical Education and Research Terms and Conditions


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