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Possible Contribution of Fibrocytes to Increased Type I Collagen Synthesis during the Early Stage of Dermal Wound Repair in Human Skin Min Sun, Peiru Wang, Toru Okubo, Jeffrey S. Orringer, John J. Voorhees, Gary J. Fisher, Yong Li Journal of Investigative Dermatology Volume 138, Issue 1, Pages (January 2018) DOI: /j.jid Copyright © 2017 The Authors Terms and Conditions
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Figure 1 A fraction of CD45+ cells express proCOL1 protein at 1 week after wounding in human skin. Double immunofluorescence staining of proCOL1 and CD45 was performed on frozen sections from (a) nonwounded, (a, b) 1 week, and (c) 3 weeks after wounding. Nuclei were stained by blue DAPI. (b) Representative high magnification image of the CD45+ cell rich area in the dermis, 1 week after wounding. Cells costained with CD45 and proCOL1 are indicated by arrows. Images are representative of nine independent experiments. proCOL1, type I procollagen. Journal of Investigative Dermatology , DOI: ( /j.jid ) Copyright © 2017 The Authors Terms and Conditions
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