1. Photodynamic Therapy for Cutaneous Proliferative Vascular Tumors in a Mouse Model 
Maritza A. Middelkamp-Hup, Ignacio Sánchez-Carpintero, MD, PhD, Sylvie Kossodo, Peter Waterman, Salvador González, Martin C. Mihm, R. Rox Anderson 
Journal of Investigative Dermatology 
Volume 121, Issue 3, Pages (September 2003)
DOI: /j x
Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

2. Figure 1
Clinical and histologic findings in a mouse model angiosarcoma. The pictures in column I show tumors grown 10 to 14 d after injection of MS1 VEGF cells. Column II shows pictures of tumors, 2 wk after treatment with increasing fluences. Columns III and IV show the morphologic changes of the excised tumor tissue, 2 wk after treatment. Note the absence of significant destructive alterations in the control group (III g and IV h). The picture of the control tumor is representative for all control tumors. Scale bar=200 μm.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

3. Figure 2
Tumor volume reduction is fluence dependent. Bars represent tumor volumes before and after treatment with PDT-BPD, and error bars represent SEM (n=29). The fluence of 0 J per cm2 indicates unirradiated tumors, only treated with BPD-MA (1 mg per kg), thus serving as control. Significant smaller volumes after treatment compared with the volumes after treatment in the control group: *p<0.05, **p≤0.01. Statistical analyses were performed using the Mann–Whitney test.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions

4. Figure 3
The skin overlying a tumor showing extensive destruction by PDT-BPD is completely normal. This observation supports the selectivity of PDT-BPD for the tumor.
Journal of Investigative Dermatology  , DOI: ( /j x)
Copyright © 2003 The Society for Investigative Dermatology, Inc Terms and Conditions