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Preliminary report on the interaction of apolipoprotein E polymorphism with aortic atherosclerosis and acute nephropathy after CABG  G.Burkhard MacKensen,

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Presentation on theme: "Preliminary report on the interaction of apolipoprotein E polymorphism with aortic atherosclerosis and acute nephropathy after CABG  G.Burkhard MacKensen,"— Presentation transcript:

1 Preliminary report on the interaction of apolipoprotein E polymorphism with aortic atherosclerosis and acute nephropathy after CABG  G.Burkhard MacKensen, MD, Madhav Swaminathan, MD, Lian K Ti, MMed, Hilary P Grocott, FRCPC, Barbara G Phillips-Bute, PhD, Joseph P Mathew, MD, Mark F Newman, MD, Carmelo A Milano, MD, Mark Stafford-Smith, FRCPC  The Annals of Thoracic Surgery  Volume 78, Issue 2, Pages (August 2004) DOI: /j.athoracsur

2 Fig 1 The midesophageal short-axis image (top) of the thoracic aorta illustrating how percentage atheroma burden (% atheroma) was calculated. Atheroma burden in each segment was calculated as the percent area of the aorta containing atheroma; (bottom) the areas A (reflecting the area of plaque) and B (reflecting the total vessel area including the plaque) were used as a ratio to calculate the percent of vessel area represented by plaque (% atheroma). Thus, % atheroma = A/(A + B) × 100%. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )

3 Fig 2 “Best fit” lines from raw data showing the relationship between atheroma burden (% ascending atheroma) and peak postoperative creatinine values (CrmaxPost) for the ascending aorta in 130 patients who underwent coronary artery bypass grafting. The data are grouped by presence or absence of the ϵ4 allele. To convert mg/dL to μmol/L, multiply the mg/dL amount by 88.4. The Annals of Thoracic Surgery  , DOI: ( /j.athoracsur )


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