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Published bySusanti Dharmawijaya Modified over 5 years ago
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Applying the Latest Data on Treat-and-Extend Strategies to Clinical Cases in nAMD
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What Clinicians Need to Know Regarding Treat-and-Extend Regimens
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Advantages of T&E Regimen Strategy
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Advantages of T&E over PRN Regimen
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Injection Schedule for the Recommended Treatment Approach in the First Year of T&E
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ALTAIR Study: Mean Change in BCVA From Baseline to Week 52
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ALTAIR Study: Maximum Interval Extension Times
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The Role of Exudation
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Results from CATT Trial: IRF
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FLUID Study: OCT SRF Fluid Determination
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Clinical Cases in nAMD
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FIRST CASE SCENARIO: Patient who had been successfully managed on a T&E regimen for some time, but develops exudation without a change in vision
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When Do You Extend The Interval Period?
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FIRST CASE SCENARIO, cont
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SECOND CASE SCENARIO: Patient who was started on a T&E regimen, had some exudation appear during the T&E regimen (eg, at 10 weeks), so the interval was shortened again; but then patient was restarted on T&E and successfully extended to 12 week injections
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PLANET Study: Aflibercept Monotherapy vs Aflibercept Plus PDT in Patients With PCV
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EVEREST II: Treatment Schedule
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SECOND CASE SCENARIO, cont
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THIRD CASE SCENARIO: Patient successfully managed on a T&E regimen but then misses appointments and shows back up 5-6 months after their last injection
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THIRD CASE SCENARIO, cont
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Concluding Remarks
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Abbreviations
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