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Chromosomal translocations and semen quality: A study on 144 male translocation carriers  Anne Mayeur, Naouel Ahdad, Laetitia Hesters, Sophie Brisset,

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Presentation on theme: "Chromosomal translocations and semen quality: A study on 144 male translocation carriers  Anne Mayeur, Naouel Ahdad, Laetitia Hesters, Sophie Brisset,"— Presentation transcript:

1 Chromosomal translocations and semen quality: A study on 144 male translocation carriers 
Anne Mayeur, Naouel Ahdad, Laetitia Hesters, Sophie Brisset, Serge Romana, Lucie Tosca, Gérard Tachdjian, Nelly Frydman  Reproductive BioMedicine Online  Volume 38, Issue 1, Pages (January 2019) DOI: /j.rbmo Copyright © Terms and Conditions

2 FigURE 1 Sperm characteristics in the control group (CTL), reciprocal translocation (RCT) and Robertsonian translocation (ROBT) carriers. (A) Percentage of normozoospermic men in the three groups (sperm morphology excluded). (B) Patients were stratified according to their translocation and to NPS-ASP categories. Good NPS-ASP (≥5 × 106), fair NPS-ASP (>1 × 106 to <5 × 106), poor NPS-ASP (>0.5×106 to ≤1×106) and very poor NPS-ASP (≤0.5×106). NPS-ASP = number of progressive spermatozoa retrieved after sperm preparation. Reproductive BioMedicine Online  , 46-55DOI: ( /j.rbmo ) Copyright © Terms and Conditions

3 FigURE 2 Proportion of good, fair, poor, and very poor NPS-ASP values for each type of Robertsonian translocation. These rearrangements originate through the translocation of acrocentric chromosomes (13, 14, 15, 21, 22). Rare translocations comprise (13q;21q)-n = 1, (13q;15q)-n = 4, (14q;15q)-n = 1, (14q;22q)-n = 1, (15q;21q)-n = 1, (15q;22q)-n = 1, (21q;22q)-n = 1. NPS-ASP categories defined as good (≥5 × 106), fair (>1 × 106 to <5 × 106), poor NPS-ASP (>0.5 × 106 to ≤1 × 106) and very poor (≤0.5 × 106). NPS-ASP = number of progressive spermatozoa retrieved after sperm preparation. Reproductive BioMedicine Online  , 46-55DOI: ( /j.rbmo ) Copyright © Terms and Conditions


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